Interactor 1: KU70 (P32807)
ATP-dependent DNA helicase II subunit 1 (EC 3.6.4.12) (ATP-dependent DNA helicase II subunit Ku70) (High affinity DNA-binding factor subunit 1)
Gene: YKU70
Interactor 2: KU80 (Q04437)
ATP-dependent DNA helicase II subunit 2 (EC 3.6.4.12) (ATP-dependent DNA helicase II subunit Ku80) (High affinity DNA-binding factor subunit 2) (Yeast Ku80)
Gene: YKU80
Species: Saccharomyces cerevisiae S288C
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.975 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11805826, 26218225, 16554755, 16429126, 29500182, 29290466, 37968396, 21852961, 24567323, 19276071, 20826334, 22088982 |
| Identification Methods | tandem affinity purification, pull down, affinity chromatography technology, x-ray crystallography |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ku~Ku, Ku~Ku_N, Ku~Ku_C, Ku_C~Ku_N, Ku_N~Ku_N |
| Common GO terms | GO:0000723 - telomere maintenance GO:0000724 - double-strand break repair via homologous recombination GO:0000725 - recombinational repair GO:0000781 - chromosome, telomeric region GO:0003684 - damaged DNA binding and 10 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Sc | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | At | |
|
|||||||||||
| + | Sp | |
|
|||||||||||
| + | Ce | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
