HitPredict

Interactor 1: MRE11 (P32829)
Double-strand break repair protein MRE11 (EC 3.1.-.-)
Gene: MRE11

Interactor 2: DNA2 (P38859)
DNA replication ATP-dependent helicase/nuclease DNA2 [Includes: DNA replication nuclease DNA2 (EC 3.1.-.-); DNA replication ATP-dependent helicase DNA2 (EC 3.6.4.12)]
Gene: DNA2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.61 0.55 0.581

The method score is based on:

Property Details
Experiments 20811460, 31390569
Identification Methods pull down, two hybrid, affinity chromatography technology
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000014 - single-stranded DNA endodeoxyribonuclease activity
GO:0000723 - telomere maintenance
GO:0000729 - DNA double-strand break processing
GO:0005634 - nucleus
GO:0006281 - DNA repair
and 1 others

more...
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024