HitPredict

Interactor 1: B1AXJ3 (B1AXJ3)
Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
Gene: Lrp8

Interactor 2: DAB1 (P97318)
Disabled homolog 1
Gene: DAB1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.705

Property	Details
Experiments	10827199, 10380922, 33572344, 15249135, 15718228
Identification Methods	two hybrid, pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0021517 - ventral spinal cord development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 832 Mm			1 588
+	Mm
		956234 LRP8_MOUSE (8-832): 0: 704: 83.22		DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00
+	Mm
		956222 VLDLR_MOUSE (8-761): 4.35e-170: 516: 42.46		DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00
+	Hs
		269133 VLDLR_HUMAN (32-344): 1.33e-38: 156: 30.51		DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50
+	Mm
		729617 LDLR_MOUSE (68-546): 2.54e-29: 127: 22.44		DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00
+	Hs
		269145 LRP8_HUMAN (4-194): 2.03e-22: 105: 23.30		DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50
+	Hs
		269134 LRP2_HUMAN (119-313): 1.46e-10: 67.5: 12.67		DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50
+	Hs
		269141 LRP1_HUMAN (7-148): 1.04e-09: 64.8: 16.88		DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50
+	Hs
		957177 LRP8_HUMAN (4-194): 2.03e-22: 105: 23.30		DAB2_HUMAN (8-584): 2.88e-39: 155: 25.47
+	Hs
		253558 LRP8_HUMAN (4-194): 2.03e-22: 105: 23.30		CAPON_HUMAN (11-299): 2.87e-36: 144: 15.11
+	Hs
		957612 LRP2_HUMAN (119-313): 1.46e-10: 67.5: 12.67		ARH_HUMAN (11-271): 2.37e-48: 172: 18.35
+	Hs
		957621 LRP2_HUMAN (119-313): 1.46e-10: 67.5: 12.67		ANS1B_HUMAN (8-229): 3.86e-44: 171: 16.81
+	Hs
		992682 LRP1_HUMAN (7-148): 1.04e-09: 64.8: 16.88		ANS1B_HUMAN (8-229): 3.86e-44: 171: 16.81
+	Hs
		270287 LRP6_HUMAN (110-272): 7.62e-12: 71.3: 20.36		DAB2_HUMAN (8-584): 2.88e-39: 155: 25.47
+	Rn
		292326 LRP2_RAT (120-341): 7.54e-10: 65.2: 13.93		DAB2_RAT (8-587): 1.04e-40: 159: 25.34
+	Hs
		957165 LRP2_HUMAN (119-313): 1.46e-10: 67.5: 12.67		DAB2_HUMAN (8-584): 2.88e-39: 155: 25.47
+	Hs
		957171 LRP1_HUMAN (7-148): 1.04e-09: 64.8: 16.88		DAB2_HUMAN (8-584): 2.88e-39: 155: 25.47
+	Rn
		88518 LRP2_RAT (120-341): 7.54e-10: 65.2: 13.93		ARH_RAT (8-271): 7.1e-42: 154: 16.30
+	Hs
		253552 LRP2_HUMAN (119-313): 1.46e-10: 67.5: 12.67		CAPON_HUMAN (11-299): 2.87e-36: 144: 15.11
+	Ce
		60768 O01768_CAEEL (1-241): 1.86e-10: 67.1: 13.93		A5JYR4_CAEEL (2-386): 2.33e-36: 144: 23.06
+	Hs
		253555 LRP1_HUMAN (7-148): 1.04e-09: 64.8: 16.88		CAPON_HUMAN (11-299): 2.87e-36: 144: 15.11