HitPredict

Interactor 1: PEP12 (P32854)
Syntaxin PEP12 (Carboxypeptidase Y-deficient protein 12) (Vacuolar protein sorting-associated protein 6) (Vacuolar protein-targeting protein 13)
Gene: PEP12

Interactor 2: TLG1 (Q03322)
t-SNARE affecting a late Golgi compartment protein 1 (Syntaxin TLG1)
Gene: TLG1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.650

The method score is based on:

Property Details
Experiments 14981247, 12453154, 15799968
Identification Methods pull down, affinity chromatography technology, biochemical, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000139 - Golgi membrane
GO:0000149 - SNARE binding
GO:0005484 - SNAP receptor activity
GO:0005768 - endosome
GO:0005829 - cytosol
and 8 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 288
Sc

1 224
+ At
+ At
+ At
+ Hs
+ At
+ Mm
+ At
+ Hs
+ Hs
+ At
+ Dm
+ Dm
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024