HitPredict

Interactor 1: STX2 (P32856)
Syntaxin-2 (Epimorphin)
Gene: STX2

Interactor 2: SYTL4 (Q96C24)
Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin)
Gene: SYTL4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24700782
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C2~SNARE, C2~Syntaxin
Common GO terms	GO:0005886 - plasma membrane GO:0006886 - intracellular protein transport GO:0006887 - exocytosis
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 288 Hs			1 671
+	Hs
		1083970 STX1A_HUMAN (1-286): 4.14e-76: 235: 64.46		SYTL4_HUMAN (1-671): 0: 587: 100.00
+	Hs
		1030179 STX3_HUMAN (1-287): 6.25e-60: 194: 63.79		SYTL4_HUMAN (1-671): 0: 587: 100.00
+	Dm
		599152 STX1A_DROME (2-282): 1.01e-72: 226: 60.56		SY65_DROME (175-654): 1.88e-82: 270: 22.00
+	Hs
		599551 STX2_HUMAN (1-288): 5.69e-82: 250: 100.00		SYT1_HUMAN (513-666): 6.03e-29: 121: 27.22
+	Mm
		192842 STX1A_MOUSE (1-287): 5.2e-78: 240: 65.63		SYT2_MOUSE (215-493): 2.34e-30: 126: 16.49
+	Rn
		699170 STX1A_RAT (1-287): 7.28e-78: 239: 65.28		RP3A_RAT (518-671): 1.13e-28: 123: 22.49
+	Rn
		600312 STX1A_RAT (1-287): 7.28e-78: 239: 65.28		SYT1_RAT (513-666): 5.95e-29: 121: 27.22
+	Hs
		599575 STX1A_HUMAN (1-286): 4.14e-76: 235: 64.46		SYT1_HUMAN (513-666): 6.03e-29: 121: 27.22
+	Dm
		1098093 STX1A_DROME (2-282): 1.01e-72: 226: 60.56		Q9U6P7_DROME (502-665): 1.34e-21: 100: 20.67
+	Hs
		599566 STX4_HUMAN (1-286): 1.23e-60: 196: 42.57		SYT1_HUMAN (513-666): 6.03e-29: 121: 27.22
+	Hs
		599569 STX3_HUMAN (1-287): 6.25e-60: 194: 63.79		SYT1_HUMAN (513-666): 6.03e-29: 121: 27.22