HitPredict

Interactor 1: RAEP (P32864)
Rab proteins geranylgeranyltransferase component A (Rab escort protein) (REP)
Gene: MRS6

Interactor 2: YPT10 (P38146)
GTP-binding protein YPT10
Gene: YPT10

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.72	1.00	0.854

Property	Details
Experiments	11283351, 11805837, 18719252
Identification Methods	two hybrid pooling approach, anti tag coimmunoprecipitation, affinity chromatography technology, two hybrid
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 603 Sc			1 199
+	Sc
		350859 RAEP_YEAST (1-603): 0: 843: 100.00		YPT1_YEAST (2-199): 6.1e-78: 233: 26.57
+	Sc
		699420 RAEP_YEAST (1-603): 0: 843: 100.00		YPT52_YEAST (6-182): 1.08e-34: 124: 40.98
+	Sc
		699419 RAEP_YEAST (1-603): 0: 843: 100.00		VPS21_YEAST (4-192): 6.67e-33: 119: 38.07
+	Sc
		699421 RAEP_YEAST (1-603): 0: 843: 100.00		YPT53_YEAST (4-169): 1.24e-32: 118: 43.43
+	Sc
		699435 RAEP_YEAST (1-603): 0: 843: 100.00		YPT6_YEAST (6-172): 4.59e-28: 106: 38.37
+	Hs
		678344 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB1A_HUMAN (2-198): 1.26e-80: 240: 27.59
+	Mm
		838709 GDIA_MOUSE (45-434): 2.77e-176: 508: 25.76		RAB1A_MOUSE (2-198): 1.26e-80: 240: 27.59
+	Hs
		678394 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB1B_HUMAN (2-199): 2.19e-79: 237: 27.72
+	Hs
		678330 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB5C_HUMAN (4-198): 6.49e-79: 236: 36.50
+	Hs
		592123 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB5A_HUMAN (4-198): 3.94e-78: 234: 35.00
+	Hs
		678343 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RB11A_HUMAN (2-198): 8.5e-76: 228: 27.96
+	Hs
		592161 GDIB_HUMAN (45-434): 6.79e-174: 502: 26.26		RAB5A_HUMAN (4-198): 3.94e-78: 234: 35.00
+	Hs
		678359 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RB11B_HUMAN (2-198): 1.64e-74: 225: 28.17
+	Hs
		678338 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB2A_HUMAN (3-191): 2.34e-73: 222: 27.08
+	Hs
		678358 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB35_HUMAN (2-199): 1.46e-73: 222: 25.74
+	Hs
		678377 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB2B_HUMAN (3-193): 3.57e-73: 222: 25.77
+	Hs
		678339 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB5B_HUMAN (6-197): 5.24e-32: 116: 38.58
+	Hs
		678402 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB6B_HUMAN (6-199): 6.84e-31: 113: 32.68
+	Hs
		592631 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB6A_HUMAN (6-199): 9.77e-30: 110: 31.53
+	Hs
		678407 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB21_HUMAN (4-160): 4.64e-29: 109: 40.99