HitPredict

Interactor 1: RAEP (P32864)
Rab proteins geranylgeranyltransferase component A (Rab escort protein) (REP)
Gene: MRS6

Interactor 2: YPT6 (Q99260)
GTP-binding protein YPT6
Gene: YPT6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.72	1.00	0.852

Property	Details
Experiments	18467557, 18719252, 22615397
Identification Methods	protein complementation assay, two hybrid, dihydrofolate reductase reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	GDI~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 603 Sc			1 215
+	Sc
		350859 RAEP_YEAST (1-603): 0: 843: 100.00		YPT1_YEAST (11-215): 1.69e-84: 250: 34.15
+	Sc
		699419 RAEP_YEAST (1-603): 0: 843: 100.00		VPS21_YEAST (7-215): 9.74e-42: 142: 38.07
+	Hs
		678336 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB8A_HUMAN (11-215): 2.51e-89: 263: 39.02
+	Hs
		678402 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB6B_HUMAN (5-215): 5.7e-89: 262: 59.54
+	Hs
		678333 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB13_HUMAN (1-214): 5.78e-85: 251: 37.85
+	Hs
		678344 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB1A_HUMAN (1-215): 1.85e-84: 250: 33.33
+	Hs
		678381 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB8B_HUMAN (1-215): 6.15e-84: 249: 38.61
+	Mm
		838709 GDIA_MOUSE (45-434): 2.77e-176: 508: 25.76		RAB1A_MOUSE (1-215): 1.85e-84: 250: 33.33
+	Hs
		678343 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RB11A_HUMAN (1-214): 2.15e-83: 248: 32.09
+	Hs
		678394 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB1B_HUMAN (7-215): 7.88e-82: 244: 33.49
+	Hs
		592631 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB6A_HUMAN (5-215): 3.69e-81: 242: 59.54
+	Hs
		678341 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB14_HUMAN (1-215): 4.81e-81: 242: 30.88
+	Hs
		678359 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RB11B_HUMAN (1-214): 3.37e-80: 240: 30.42
+	Hs
		678377 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB2B_HUMAN (7-214): 2.25e-80: 240: 32.41
+	Hs
		678393 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB6C_HUMAN (5-215): 6.19e-74: 225: 54.88
+	Hs
		678351 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB31_HUMAN (7-213): 8.1e-47: 154: 39.90
+	Hs
		678330 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB5C_HUMAN (4-196): 2.82e-45: 151: 38.00
+	Hs
		592123 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB5A_HUMAN (4-213): 3.49e-44: 148: 37.14
+	Hs
		678339 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RAB5B_HUMAN (8-213): 6.68e-43: 145: 37.86
+	Hs
		678408 GDIA_HUMAN (45-434): 1.03e-176: 509: 26.01		RB22A_HUMAN (7-174): 1.11e-41: 141: 41.07