Interactor 1: TIM23 (P32897)
Mitochondrial import inner membrane translocase subunit TIM23 (Membrane import machinery protein MIM23) (Mitochondrial protein import protein 3) (Mitochondrial protein import protein MAS6)
Gene: TIM23

Interactor 2: TIM50 (Q02776)
Mitochondrial import inner membrane translocase subunit TIM50
Gene: TIM50

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.99 0.60 0.771

The method score is based on:

Property Details
Experiments 12437925, 25263020, 23403928, 15797382, 15878866, 30765764, 32130909, 19017642, 17959826, 37748811, 37968396, 21969381, 22065641, 24061477, 14517234, 14532110, 12437924, 14981507, 25765297, 15992824 and 21 others

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Identification Methods coimmunoprecipitation, nuclear magnetic resonance, cosedimentation through density gradient, two hybrid, affinity chromatography technology, pull down, biochemical, cross-linking study, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005744 - TIM23 mitochondrial import inner membrane translocase complex
GO:0006886 - intracellular protein transport
GO:0030150 - protein import into mitochondrial matrix
and 2 others

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Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 222
Sc

1 476
+ Sc
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024