Interactor 1: PRP45 (P28004)
Pre-mRNA-processing protein 45
Gene: PRP45

Interactor 2: CEF1 (Q03654)
Pre-mRNA-splicing factor CEF1 (PRP nineteen-associated complex protein 85) (PRP19-associated complex protein 85)
Gene: CEF1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.947

The method score is based on:

Property Details
Experiments 11805826, 37968396, 11884590, 16429126, 29146870, 30879786
Identification Methods tandem affinity purification, affinity chromatography technology, pull down, biochemical
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Myb_Cef~SKIP_SNW, Myb_DNA-binding~SKIP_SNW
Common GO terms GO:0000350 - generation of catalytic spliceosome for second transesterification step
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0071006 - U2-type catalytic step 1 spliceosome
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 379
Sc

1 590
+ Hs
+ Sp

Service provided by Combinatics, Japan

Last updated: 11Aug2025