HitPredict

Interactor 1: SH3GH (B1V8A0)
Endophilin-A homolog (Endophilin-1 homolog) (Uncoordinated protein 57)
Gene: unc-57

Interactor 2: G5EBN5 (G5EBN5)
BRO1 domain-containing protein (Enhancer of glp-1)
Gene: ego-2

Species: Caenorhabditis elegans

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	23549480
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 381 Ce			1 1492
+	Mm
		1143918 SH3G1_MOUSE (1-380): 6e-79: 248: 44.76		PDC6I_MOUSE (14-896): 0: 575: 18.40
+	Mm
		1143926 SH3G2_MOUSE (1-380): 9.84e-77: 242: 43.46		PDC6I_MOUSE (14-896): 0: 575: 18.40
+	Hs
		1260385 SH3G1_HUMAN (1-380): 9.5e-80: 251: 44.76		PDC6I_HUMAN (14-896): 5.97e-180: 560: 18.62
+	Hs
		1260386 SH3G2_HUMAN (1-380): 2.02e-77: 244: 43.19		PDC6I_HUMAN (14-896): 5.97e-180: 560: 18.62
+	Ce
		70028 SH3GH_CAEEL (1-381): 4.62e-83: 259: 100.00		ALXA_CAEEL (16-881): 2.16e-140: 455: 18.78
+	Mm
		1141174 GRB2_MOUSE (325-376): 5.06e-12: 66.8: 35.85		PDC6I_MOUSE (14-896): 0: 575: 18.40
+	Hs
		1191850 SH3R1_HUMAN (281-374): 1.91e-11: 67.7: 17.71		PDC6I_HUMAN (14-896): 5.97e-180: 560: 18.62
+	Dm
		1180080 Q7K4D1_DROME (196-380): 2.91e-19: 91.8: 23.83		Q9VB05_DROME (14-867): 1.52e-140: 454: 16.84
+	Dm
		1342129 Q9NHP2_DROME (196-380): 2.86e-19: 91.8: 23.83		Q9VB05_DROME (14-867): 1.52e-140: 454: 16.84
+	Ce
		666203 SEM5_CAEEL (325-374): 3.83e-19: 87.2: 50.00		ALXA_CAEEL (16-881): 2.16e-140: 455: 18.78
+	Dm
		993211 GRAP_DROME (325-374): 1.75e-18: 84.9: 46.00		Q9VUH6_DROME (1-1447): 1.12e-133: 457: 18.27
+	Hs
		203248 SH3G1_HUMAN (1-380): 9.5e-80: 251: 44.76		SYNJ1_HUMAN (826-1260): 7.01e-11: 69.4: 14.22
+	Mm
		88460 SH3G3_MOUSE (1-380): 4.87e-78: 245: 43.98		D3Z656_MOUSE (1130-1488): 1.28e-10: 68.7: 12.90
+	Hs
		203249 SH3G2_HUMAN (1-380): 2.02e-77: 244: 43.19		SYNJ1_HUMAN (826-1260): 7.01e-11: 69.4: 14.22
+	Mm
		88459 SH3G2_MOUSE (1-380): 9.84e-77: 242: 43.46		D3Z656_MOUSE (1130-1488): 1.28e-10: 68.7: 12.90
+	Hs
		1307434 SH3G2_HUMAN (1-380): 2.02e-77: 244: 43.19		PTN23_HUMAN (1091-1488): 3.17e-09: 64: 12.29
+	Hs
		203262 PACN2_HUMAN (3-378): 9.03e-43: 157: 12.41		SYNJ1_HUMAN (826-1260): 7.01e-11: 69.4: 14.22
+	Hs
		203251 PACN1_HUMAN (4-377): 1.16e-40: 150: 14.58		SYNJ1_HUMAN (826-1260): 7.01e-11: 69.4: 14.22
+	Hs
		203224 MYO1E_HUMAN (252-377): 3.64e-25: 109: 33.33		SYNJ1_HUMAN (826-1260): 7.01e-11: 69.4: 14.22
+	Hs
		1021699 MYO1E_HUMAN (252-377): 3.64e-25: 109: 33.33		CLIC6_HUMAN (787-1192): 8.92e-09: 62.4: 16.52