HitPredict

Interactor 1: B1WBX9 (B1WBX9)
Cytokine-inducible SH2-containing protein
Gene: Cish

Interactor 2: GHR (P16310)
Growth hormone receptor (GH receptor) (Somatotropin receptor) [Cleaved into: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)]
Gene: GHR

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	12586763
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 257 Rn			1 638
+	Hs
		500974 CISH_HUMAN (1-257): 8.8e-67: 209: 88.37		GHR_HUMAN (1-637): 0: 768: 69.80
+	Hs
		560479 CISH_HUMAN (1-257): 8.8e-67: 209: 88.37		PRLR_HUMAN (45-526): 1.51e-93: 302: 27.92
+	Hs
		562584 CISH_HUMAN (1-257): 8.8e-67: 209: 88.37		IL7RA_HUMAN (127-477): 1.47e-72: 242: 21.37
+	Hs
		411991 FYN_HUMAN (37-233): 8.51e-47: 165: 14.09		IL7RA_HUMAN (127-477): 1.47e-72: 242: 21.37
+	Hs
		412036 FYN_HUMAN (37-233): 8.51e-47: 165: 14.09		EPHA3_HUMAN (3-297): 4.72e-65: 232: 12.62
+	Hs
		412104 FYN_HUMAN (37-233): 8.51e-47: 165: 14.09		EPHA5_HUMAN (13-292): 2.78e-64: 231: 15.07
+	Mm
		540271 CISH_MOUSE (1-257): 9.3e-73: 224: 96.11		EPOR_MOUSE (6-254): 6.8e-41: 158: 16.86
+	Mm
		763386 FYN_MOUSE (37-233): 8e-47: 165: 14.09		EPHA4_MOUSE (4-297): 7.13e-59: 215: 12.38
+	Hs
		412037 FYN_HUMAN (37-233): 8.51e-47: 165: 14.09		EPHA8_HUMAN (1-272): 2.51e-58: 213: 13.03
+	Hs
		412105 FYN_HUMAN (37-233): 8.51e-47: 165: 14.09		EPHA4_HUMAN (4-297): 3.09e-58: 213: 11.44
+	Hs
		1303311 CISH_HUMAN (1-257): 8.8e-67: 209: 88.37		CSF3R_HUMAN (17-266): 1.44e-42: 166: 15.71
+	Hs
		581173 CISH_HUMAN (1-257): 8.8e-67: 209: 88.37		EPOR_HUMAN (6-254): 9.18e-43: 163: 18.82
+	Hs
		412103 FYN_HUMAN (37-233): 8.51e-47: 165: 14.09		EPHB3_HUMAN (13-270): 3.1e-54: 202: 14.87
+	Hs
		412007 FYN_HUMAN (37-233): 8.51e-47: 165: 14.09		EPHA1_HUMAN (13-269): 1.39e-42: 166: 10.41
+	Hs
		442875 HCK_HUMAN (4-233): 3.74e-47: 165: 12.99		CSF3R_HUMAN (17-266): 1.44e-42: 166: 15.71
+	Hs
		412029 FYN_HUMAN (37-233): 8.51e-47: 165: 14.09		CNTFR_HUMAN (2-265): 1.04e-42: 160: 17.16
+	Mm
		435879 HCK_MOUSE (4-233): 3.3e-47: 165: 14.23		CSF3R_MOUSE (42-257): 1.96e-38: 154: 15.56
+	Mm
		645935 CISH_MOUSE (1-257): 9.3e-73: 224: 96.11		IL3B2_MOUSE (54-280): 2.37e-12: 72.2: 14.06
+	Mm
		817306 CISH_MOUSE (1-257): 9.3e-73: 224: 96.11		LEPR_MOUSE (112-259): 4.68e-12: 71.4: 19.61
+	Hs
		442787 HCK_HUMAN (4-233): 3.74e-47: 165: 12.99		IL6RB_HUMAN (37-373): 2.08e-15: 82.2: 14.45