Interactor 1: SMC1 (P32908)
Structural maintenance of chromosomes protein 1 (DA-box protein SMC1)
Gene: SMC1

Interactor 2: SCC3 (P40541)
Cohesin subunit SCC3 (Irregular cell behavior protein 1)
Gene: IRR1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 0.60 0.746

The method score is based on:

Property Details
Experiments 10882066, 9990856, 17660750, 37166686, 21441928, 31807710, 34259632, 37968396
Identification Methods coimmunoprecipitation, affinity chromatography technology, fluorescent resonance energy transfer, biochemical, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0007062 - sister chromatid cohesion
GO:0007064 - mitotic sister chromatid cohesion
GO:0008278 - cohesin complex
GO:0030892 - mitotic cohesin complex
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1225
Sc

1 1150
+ Hs
+ Xl
+ Hs
+ Mm
+ Mm
+ Xl
+ Hs
+ Mm
+ Hs
+ Xl
+ Xl
+ Mm
+ Mm
+ Mm
+ Xl
+ Hs
+ Sp
+ Sp
+ Sp
+ Sp

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Last updated: 15 Jul 2024