HitPredict

Interactor 1: SUI1 (P32911)
Eukaryotic translation initiation factor eIF-1 (Protein translation factor SUI1)
Gene: SUI1

Interactor 2: IF5 (P38431)
Eukaryotic translation initiation factor 5 (eIF-5)
Gene: TIF5

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	1.00	0.977

Property	Details
Experiments	12861028, 15145951, 15377664, 30576497, 21745818, 11018020, 15964804, 15838098, 24335188, 37968396, 16990799
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	SUI1~eIF-5_eIF-2B
Common GO terms	GO:0001731 - formation of translation preinitiation complex GO:0003743 - translation initiation factor activity GO:0031369 - translation initiation factor binding GO:0043614 - multi-eIF complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 108 Sc			1 405
+	Hs
		783574 EIF1_HUMAN (2-108): 1.05e-46: 147: 56.76		IF5_HUMAN (1-395): 1.09e-129: 381: 36.66
+	Sc
		447174 SUI1_YEAST (1-108): 3.49e-56: 171: 100.00		IF2B_YEAST (3-130): 9.03e-44: 155: 25.93
+	Sc
		691732 SUI1_YEAST (1-108): 3.49e-56: 171: 100.00		EI2BE_YEAST (129-396): 1.81e-10: 64.9: 15.52