Interactor 1: SC61A (P32915)
Protein transport protein SEC61 (Sec61 complex subunit SEC61) (Sec61 complex subunit alpha)
Gene: SEC61

Interactor 2: SEC66 (P33754)
Translocation protein SEC66 (Protein HSS1) (Sec62/63 complex 31.5 kDa subunit)
Gene: SEC66

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.917

The method score is based on:

Property Details
Experiments 16093310, 37968396, 30682149, 21454595, 8612571
Identification Methods ubiquitin reconstruction, affinity chromatography technology, protein complementation assay, pull down, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Sec66~SecY
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0030867 - rough endoplasmic reticulum membrane
GO:0031204 - post-translational protein targeting to membrane, translocation
GO:0071256 - translocon complex
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 480
Sc

1 206
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024