Interactor 1: SRPR (P32916)
Signal recognition particle receptor subunit alpha homolog (SR-alpha) (Docking protein alpha) (DP-alpha)
Gene: SRP101

Interactor 2: SRPB (P36057)
Signal recognition particle receptor subunit beta (SR-beta)
Gene: SRP102

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 16627619, 9679135, 11805826, 16429126, 18719252, 37968396, 20826334, 22940862, 12654246
Identification Methods molecular sieving, coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, two hybrid, x-ray crystallography
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SRP54~SRPRB, SRPRB~SRX
Common GO terms GO:0005047 - signal recognition particle binding
GO:0005525 - GTP binding
GO:0005785 - signal recognition particle receptor complex
GO:0005789 - endoplasmic reticulum membrane
GO:0006617 - SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
and 2 others

more...

Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 621
Sc

1 244
+ Dm
+ Hs
+ Hs
+ Tt
+ Hs
+ Sc

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Last updated: 15 Jul 2024