Interactor 1: CGL (P32929)
Cystathionine gamma-lyase (CGL) (CSE) (EC 4.4.1.1) (Cysteine desulfhydrase) (Cysteine-protein sulfhydrase) (Gamma-cystathionase) (Homocysteine desulfhydrase) (EC 4.4.1.2)
Gene: CTH

Interactor 2: CGL (P32929)
Cystathionine gamma-lyase (CGL) (CSE) (EC 4.4.1.1) (Cysteine desulfhydrase) (Cysteine-protein sulfhydrase) (Gamma-cystathionase) (Homocysteine desulfhydrase) (EC 4.4.1.2)
Gene: CTH

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.931

The method score is based on:

Property Details
Experiments 25416956, 16189514, 32296183, unassigned1304, 34112687
Identification Methods two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach, mammalian protein protein interaction trap, molecular sieving, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cys_Met_Meta_PP~Cys_Met_Meta_PP
Common GO terms GO:0004123 - cystathionine gamma-lyase activity
GO:0005516 - calmodulin binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006534 - cysteine metabolic process
and 19 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 405
Hs

1 405
+ Pa
+ Sc
+ Sc
+ Sc
+ Sc
+ Sp
+ Sc

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Last updated: 15 Jul 2024