HitPredict

Interactor 1: YPT7 (P32939)
Ypt/Rab-type GTPase YPT7 (Ypt7p) (Vacuolar morphology protein 4)
Gene: YPT7

Interactor 2: VAM6 (Q07468)
Vacuolar morphogenesis protein 6 (Vacuolar protein sorting-associated protein 39)
Gene: VAM6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	0.60	0.759

Property	Details
Experiments	25026036, 11062257, 29870720, 33513092, 18809726, 21325627, 10725336, 10944212, 27852901, 30269949, 19748353, 20604902
Identification Methods	affinity chromatography technology, pull down, two hybrid
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000324 - fungal-type vacuole GO:0000329 - fungal-type vacuole membrane GO:0016192 - vesicle-mediated transport GO:0034727 - piecemeal microautophagy of the nucleus GO:1990816 - vacuole-mitochondrion membrane contact site
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 208 Sc			1 1049
+	Hs
		833138 RAB7A_HUMAN (1-208): 8.09e-90: 263: 61.91		VPS41_HUMAN (539-1046): 2.5e-91: 312: 15.41
+	Hs
		845170 RAB7A_HUMAN (1-208): 8.09e-90: 263: 61.91		VPS39_HUMAN (544-1019): 7.77e-91: 312: 23.84
+	Dm
		284082 RAB7_DROME (1-208): 3.71e-87: 257: 58.10		VPS39_DROME (589-1017): 3.69e-86: 299: 23.45
+	Hs
		845237 RAB7A_HUMAN (1-208): 8.09e-90: 263: 61.91		VPS11_HUMAN (605-1031): 4.31e-77: 274: 14.22
+	Hs
		845311 RAB7A_HUMAN (1-208): 8.09e-90: 263: 61.91		VPS18_HUMAN (547-1017): 2.63e-68: 249: 13.35
+	Hs
		914349 RB11A_HUMAN (2-208): 2.49e-72: 220: 29.17		VPS11_HUMAN (605-1031): 4.31e-77: 274: 14.22
+	Hs
		914418 RB11A_HUMAN (2-208): 2.49e-72: 220: 29.17		VPS18_HUMAN (547-1017): 2.63e-68: 249: 13.35
+	Hs
		845725 RAB9A_HUMAN (5-208): 5.19e-61: 190: 48.53		VPS11_HUMAN (605-1031): 4.31e-77: 274: 14.22
+	Sc
		653798 YPT7_YEAST (1-208): 1.11e-78: 235: 100.00		PEP3_YEAST (628-1037): 3.82e-56: 212: 13.40
+	Hs
		845782 RAB9A_HUMAN (5-208): 5.19e-61: 190: 48.53		VPS18_HUMAN (547-1017): 2.63e-68: 249: 13.35
+	Sc
		619689 YPT7_YEAST (1-208): 1.11e-78: 235: 100.00		VPS3_YEAST (544-967): 2.45e-51: 198: 14.32
+	Sc
		701775 YPT7_YEAST (1-208): 1.11e-78: 235: 100.00		VPS41_YEAST (643-984): 1.07e-37: 155: 12.61
+	Hs
		845067 RAB7A_HUMAN (1-208): 8.09e-90: 263: 61.91		VPS8_HUMAN (502-1021): 1.6e-13: 77.5: 11.05
+	Hs
		914209 RB11A_HUMAN (2-208): 2.49e-72: 220: 29.17		VPS8_HUMAN (502-1021): 1.6e-13: 77.5: 11.05
+	Hs
		845603 RAB9A_HUMAN (5-208): 5.19e-61: 190: 48.53		VPS8_HUMAN (502-1021): 1.6e-13: 77.5: 11.05