HitPredict

Interactor 1: YPT7 (P32939)
Ypt/Rab-type GTPase YPT7 (Ypt7p) (Vacuolar morphology protein 4)
Gene: YPT7

Interactor 2: GYP1 (Q08484)
GTPase-activating protein GYP1 (GAP for YPT1)
Gene: GYP1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	9452439
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	GO:0005739 - mitochondrion GO:0016192 - vesicle-mediated transport
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 208 Sc			1 637
+	Sc
		350927 YPT1_YEAST (1-207): 2.19e-73: 222: 32.39		GYP1_YEAST (1-637): 1.25e-172: 507: 100.00
+	Hs
		845097 RAB7A_HUMAN (1-208): 8.09e-90: 263: 61.91		TBC15_HUMAN (128-574): 2.24e-82: 275: 18.03
+	Hs
		894809 RAB8A_HUMAN (1-206): 1.75e-80: 240: 36.23		TBC17_HUMAN (3-577): 1.03e-87: 288: 15.64
+	Hs
		918951 RAB1A_HUMAN (1-207): 3.26e-79: 237: 36.36		TBC17_HUMAN (3-577): 1.03e-87: 288: 15.64
+	Hs
		894747 RAB8A_HUMAN (1-206): 1.75e-80: 240: 36.23		TBC9B_HUMAN (142-630): 3.63e-81: 280: 14.06
+	Hs
		894778 RAB8A_HUMAN (1-206): 1.75e-80: 240: 36.23		TBC15_HUMAN (128-574): 2.24e-82: 275: 18.03
+	Os
		1130874 Q7XHP7_ORYSJ (4-208): 2.9e-74: 225: 36.84		Q5SMT0_ORYSJ (65-563): 1.13e-86: 286: 16.37
+	Os
		1130875 Q84TA8_ORYSJ (4-207): 9.85e-74: 223: 36.06		Q5SMT0_ORYSJ (65-563): 1.13e-86: 286: 16.37
+	Hs
		845127 RAB7A_HUMAN (1-208): 8.09e-90: 263: 61.91		TBCD5_HUMAN (198-619): 1.03e-70: 246: 13.53
+	Hs
		914391 RB11A_HUMAN (2-208): 2.49e-72: 220: 29.17		TB22B_HUMAN (101-546): 2.21e-88: 285: 30.85
+	Hs
		894727 RAB8A_HUMAN (1-206): 1.75e-80: 240: 36.23		TBC8B_HUMAN (133-631): 4.91e-74: 259: 14.82
+	Hs
		914423 RB11A_HUMAN (2-208): 2.49e-72: 220: 29.17		TBC14_HUMAN (16-565): 1.54e-81: 273: 13.63
+	Hs
		233036 RB11A_HUMAN (2-208): 2.49e-72: 220: 29.17		TBC12_HUMAN (41-565): 1.33e-80: 272: 14.92
+	Hs
		321281 RB11A_HUMAN (2-208): 2.49e-72: 220: 29.17		TBCD8_HUMAN (110-637): 1.37e-73: 258: 11.97
+	Hs
		914176 RB11A_HUMAN (2-208): 2.49e-72: 220: 29.17		TBCD1_HUMAN (56-627): 1.06e-72: 256: 15.20
+	Hs
		914259 RB11A_HUMAN (2-208): 2.49e-72: 220: 29.17		TBCD5_HUMAN (198-619): 1.03e-70: 246: 13.53
+	Ce
		1088965 Q23146_CAEEL (1-208): 1.88e-87: 258: 57.82		Q17491_CAEEL (271-509): 4.67e-34: 139: 18.64
+	Sc
		701789 YPT7_YEAST (1-208): 1.11e-78: 235: 100.00		GYP7_YEAST (276-506): 7.81e-39: 154: 19.64
+	Hs
		845109 RAB7A_HUMAN (1-208): 8.09e-90: 263: 61.91		TB22A_HUMAN (562-636): 2.43e-10: 65.2: 40.79
+	Hs
		195593 RAB9A_HUMAN (5-208): 5.19e-61: 190: 48.53		SGSM2_HUMAN (334-516): 1.67e-26: 117: 17.39