HitPredict

Interactor 1: C2TA (P33076)
MHC class II transactivator (CIITA) (EC 2.3.1.-) (EC 2.7.11.1)
Gene: CIITA

Interactor 2: RFX5 (P48382)
DNA-binding protein RFX5 (Regulatory factor X 5)
Gene: RFX5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 0.60 0.727

The method score is based on:

Property Details
Experiments 26871568, 11003667, 9177217, 12697811, 18437201, 10938133
Identification Methods affinity chromatography technology, two hybrid, far western blotting, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005654 - nucleoplasm
GO:0045348 - positive regulation of MHC class II biosynthetic process
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 1130
Hs

1 616
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024