Interactor 1: C2TA (P33076)
MHC class II transactivator (CIITA) (EC 2.3.1.-) (EC 2.7.11.1)
Gene: CIITA

Interactor 2: SMCA4 (P51532)
Transcription activator BRG1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA4) (BRG1-associated factor 190A) (BAF190A) (Mitotic growth and transcription activator) (Protein BRG-1) (Protein brahma homolog 1) (SNF2-beta) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4)
Gene: SMARCA4

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 0.60 0.646

The method score is based on:

Property Details
Experiments 12077331, 16195385, 18500344
Identification Methods pull down, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003713 - transcription coactivator activity
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0045892 - negative regulation of DNA-templated transcription
and 2 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1130
Hs

1 1647
+ Hs
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024