HitPredict

Interactor 1: C2TA (P33076)
MHC class II transactivator (CIITA) (EC 2.3.1.-) (EC 2.7.11.1)
Gene: CIITA

Interactor 2: PRS8 (P62195)
26S proteasome regulatory subunit 8 (26S proteasome AAA-ATPase subunit RPT6) (Proteasome 26S subunit ATPase 5) (Proteasome subunit p45) (Thyroid hormone receptor-interacting protein 1) (TRIP1) (p45/SUG)
Gene: PSMC5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.664

The method score is based on:

Property Details
Experiments 18215421, 26871568, 20351748
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0045892 - negative regulation of DNA-templated transcription
GO:0045893 - positive regulation of DNA-templated transcription
and 1 others

more...
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1130
Hs

1 406
+ Hs
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024