HitPredict

Interactor 1: CADH5 (P33151)
Cadherin-5 (7B4 antigen) (Vascular endothelial cadherin) (VE-cadherin) (CD antigen CD144)
Gene: CDH5

Interactor 2: TMTC3 (Q6ZXV5)
Protein O-mannosyl-transferase TMTC3 (EC 2.4.1.109) (Protein SMILE) (Transmembrane O-mannosyltransferase targeting cadherins 3) (Transmembrane and tetratricopeptide repeat-containing 3)
Gene: TMTC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 784 Hs			1 915
+	Hs
		1173523 PCDB7_HUMAN (1-492): 2.07e-91: 305: 21.54		TMTC3_HUMAN (1-915): 0: 839: 100.00
+	Hs
		522058 CADH1_HUMAN (26-780): 0: 590: 31.71		TMTC2_HUMAN (319-525): 7.77e-12: 71.4: 15.31
+	Hs
		1028130 PCDB3_HUMAN (55-674): 3.43e-117: 374: 20.18		DNJC3_HUMAN (706-894): 1.45e-12: 73.3: 8.42
+	Hs
		1232162 PCDB3_HUMAN (55-674): 3.43e-117: 374: 20.18		TMTC2_HUMAN (319-525): 7.77e-12: 71.4: 15.31
+	Hs
		877540 CADH8_HUMAN (1-469): 2.58e-86: 292: 22.75		TMTC4_HUMAN (705-894): 2.95e-18: 91.8: 13.57
+	Hs
		1232163 PCDBB_HUMAN (1-486): 6.33e-93: 309: 21.37		TMTC2_HUMAN (319-525): 7.77e-12: 71.4: 15.31
+	Hs
		1028129 PCDB7_HUMAN (1-492): 2.07e-91: 305: 21.54		DNJC3_HUMAN (706-894): 1.45e-12: 73.3: 8.42
+	Hs
		1232161 PCDB7_HUMAN (1-492): 2.07e-91: 305: 21.54		TMTC2_HUMAN (319-525): 7.77e-12: 71.4: 15.31