HitPredict

Interactor 1: KINH (P33176)
Kinesin-1 heavy chain (Conventional kinesin heavy chain) (Ubiquitous kinesin heavy chain) (UKHC)
Gene: KIF5B

Interactor 2: KLC1 (Q07866)
Kinesin light chain 1 (KLC 1)
Gene: KLC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.754

Property	Details
Experiments	26496610, 12475239, 35271311, 37071682, 28514442, 16760430, 9624122, 10491391, 33961781
Identification Methods	affinity chromatography technology, pull down, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005871 - kinesin complex GO:0005874 - microtubule GO:0007018 - microtubule-based movement GO:0016020 - membrane and 1 others more... GO:0035617 - stress granule disassembly
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 963 Hs			1 573
+	Hs
		702983 KINH_HUMAN (1-963): 5.26e-144: 455: 100.00		KLC4_HUMAN (5-571): 4.27e-99: 315: 68.53
+	Hs
		702974 KINH_HUMAN (1-963): 5.26e-144: 455: 100.00		KLC2_HUMAN (5-571): 7.66e-95: 304: 68.43
+	Hs
		101750 KINH_HUMAN (1-963): 5.26e-144: 455: 100.00		F8W6L3_HUMAN (336-567): 8.43e-21: 98.2: 21.25
+	Hs
		702921 KINH_HUMAN (1-963): 5.26e-144: 455: 100.00		KLC3_HUMAN (376-571): 6.96e-13: 73.1: 17.65
+	Hs
		174664 KINH_HUMAN (1-963): 5.26e-144: 455: 100.00		OGT1_HUMAN (382-531): 4.66e-12: 71.2: 13.33
+	Hs
		231604 KIF1B_HUMAN (4-836): 4.2e-112: 382: 23.49		TMTC1_HUMAN (336-566): 2.77e-18: 90.8: 15.88
+	Hs
		1160005 KI13B_HUMAN (4-760): 3.86e-116: 394: 23.32		KLC3_HUMAN (376-571): 6.96e-13: 73.1: 17.65
+	Hs
		992334 KIF5A_HUMAN (599-962): 8.85e-14: 77.9: 11.72		KLC1_HUMAN (1-573): 2.46e-113: 350: 100.00
+	Mm
		1143114 KINH_MOUSE (680-963): 1.95e-11: 70.2: 9.60		Q8CD76_MOUSE (1-571): 1.06e-113: 353: 95.10
+	Mm
		702846 KIF5A_MOUSE (575-960): 4.34e-11: 69.1: 8.11		Q8CD76_MOUSE (1-571): 1.06e-113: 353: 95.10
+	Hs
		229856 KIF5C_HUMAN (658-961): 7.72e-11: 68.3: 12.62		KLC1_HUMAN (1-573): 2.46e-113: 350: 100.00
+	Hs
		229891 KIF5C_HUMAN (658-961): 7.72e-11: 68.3: 12.62		KLC4_HUMAN (5-571): 4.27e-99: 315: 68.53
+	Hs
		1017559 KIF5A_HUMAN (599-962): 8.85e-14: 77.9: 11.72		KLC2_HUMAN (5-571): 7.66e-95: 304: 68.43
+	Hs
		229887 KIF5C_HUMAN (658-961): 7.72e-11: 68.3: 12.62		KLC2_HUMAN (5-571): 7.66e-95: 304: 68.43
+	Hs
		253263 KI21B_HUMAN (251-860): 6.16e-14: 78.7: 9.46		TMTC3_HUMAN (184-572): 1.42e-31: 132: 12.76
+	Rn
		881490 KINH_RAT (680-963): 2.5e-11: 69.8: 9.27		OGT1_RAT (31-384): 1.51e-29: 126: 13.08
+	Ce
		712252 KINH_CAEEL (578-913): 2.31e-14: 79.8: 27.99		KLC_CAEEL (336-573): 3.18e-22: 102: 21.67
+	Ce
		712255 KINH_CAEEL (578-913): 2.31e-14: 79.8: 27.99		Q21592_CAEEL (312-571): 4.83e-16: 83.1: 15.91
+	Hs
		1017539 KIF5A_HUMAN (599-962): 8.85e-14: 77.9: 11.72		KLC3_HUMAN (376-571): 6.96e-13: 73.1: 17.65
+	Hs
		229869 KIF5C_HUMAN (658-961): 7.72e-11: 68.3: 12.62		KLC3_HUMAN (376-571): 6.96e-13: 73.1: 17.65