HitPredict

Interactor 1: KINH (P33176)
Kinesin-1 heavy chain (Conventional kinesin heavy chain) (Ubiquitous kinesin heavy chain) (UKHC)
Gene: KIF5B

Interactor 2: LMTK2 (Q8IWU2)
Serine/threonine-protein kinase LMTK2 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase 2) (Brain-enriched kinase) (hBREK) (CDK5/p35-regulated kinase) (CPRK) (Kinase/phosphatase/inhibitor 2) (Lemur tyrosine kinase 2) (Serine/threonine-protein kinase KPI-2)
Gene: LMTK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0016020 - membrane GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 963 Hs			1 1503
+	Hs
		229875 KIF5C_HUMAN (658-961): 7.72e-11: 68.3: 12.62		LMTK2_HUMAN (1-1503): 0: 1232: 100.00
+	Hs
		229870 KIF5C_HUMAN (658-961): 7.72e-11: 68.3: 12.62		LMTK1_HUMAN (14-1500): 0: 702: 29.02
+	Hs
		384537 KIF11_HUMAN (8-877): 3.01e-160: 500: 26.43		NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33
+	Hs
		385776 KIF3A_HUMAN (7-594): 1.56e-155: 476: 33.22		NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33
+	Hs
		384364 KINH_HUMAN (1-963): 5.26e-144: 455: 100.00		NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33
+	Hs
		385569 KI13B_HUMAN (4-760): 3.86e-116: 394: 23.32		NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33
+	Hs
		384730 KIF1A_HUMAN (4-671): 3.1e-113: 384: 24.82		NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33
+	Hs
		435756 KI13A_HUMAN (4-764): 1.11e-106: 366: 23.53		IGF1R_HUMAN (131-399): 1.23e-33: 144: 33.33
+	Mm
		949301 KINH_MOUSE (680-963): 1.95e-11: 70.2: 9.60		TNIK_MOUSE (113-1179): 3.62e-128: 434: 12.84
+	Mm
		702836 KIF5A_MOUSE (575-960): 4.34e-11: 69.1: 8.11		TNIK_MOUSE (113-1179): 3.62e-128: 434: 12.84
+	Mm
		659992 KIF5C_MOUSE (659-962): 1.3e-10: 67.5: 12.34		TNIK_MOUSE (113-1179): 3.62e-128: 434: 12.84
+	Hs
		229833 KIF5C_HUMAN (658-961): 7.72e-11: 68.3: 12.62		FGFR1_HUMAN (36-471): 9.49e-119: 395: 21.20
+	Hs
		166354 KIF3B_HUMAN (44-332): 1.37e-59: 219: 48.98		NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33
+	Hs
		385083 KI21A_HUMAN (591-962): 8.18e-12: 71.8: 8.21		NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33
+	Mm
		546301 KINH_MOUSE (680-963): 1.95e-11: 70.2: 9.60		NTRK2_MOUSE (119-410): 6.45e-37: 153: 33.99
+	Hs
		411368 KIF5A_HUMAN (599-962): 8.85e-14: 77.9: 11.72		INSR_HUMAN (93-407): 2.85e-34: 145: 32.82
+	Hs
		229829 KIF5C_HUMAN (658-961): 7.72e-11: 68.3: 12.62		NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33
+	Hs
		309273 KIF4A_HUMAN (565-918): 6.06e-09: 62.1: 16.58		NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33