Interactor 1: UBC6 (P33296)
Ubiquitin-conjugating enzyme E2 6 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 6) (Ubiquitin carrier protein UBC6) (Ubiquitin-protein ligase UBC6)
Gene: UBC6
Interactor 2: DOA10 (P40318)
ERAD-associated E3 ubiquitin-protein ligase DOA10 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase DOA10)
Gene: SSM4
Species: Saccharomyces cerevisiae S288C
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.91 | 0.60 | 0.743 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25519137, 27570077, 32588820, 36325070, 38195637, 38467638, 16179953 |
| Identification Methods | protein complementation assay, enzymatic study, pull down, affinity chromatography technology, x-ray crystallography, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0004842 - ubiquitin-protein transferase activity GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0036503 - ERAD pathway |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
