HitPredict

Interactor 1: PRS6B (P33298)
26S proteasome regulatory subunit 6B homolog (Protein YNT1) (Tat-binding homolog 2)
Gene: RPT3

Interactor 2: PRS7 (P33299)
26S proteasome regulatory subunit 7 homolog (Protein CIM5) (Tat-binding homolog 3)
Gene: RPT1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 11805826, 24013205, 11805837, 19412160, 26301997, 9724628, 18467557, 37968396, 17082762, 16429126, 28137839, 36621624, 31778111, 15917626, 23644457
Identification Methods tandem affinity purification, affinity chromatography technology, anti tag coimmunoprecipitation, pull down, biochemical, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA~AAA, AAA~AAA_lid_3, AAA~Prot_ATP_ID_OB
Common GO terms GO:0000502 - proteasome complex
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
and 6 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 428
Sc

1 467
+ At
+ At
+ At
+ At
+ At
+ Dm
+ At
+ Dm
+ Hs
+ Dm
+ Dm
+ At
+ Dm
+ Sc
+ Hs
+ Rn
+ At
+ Sc
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024