HitPredict

Interactor 1: PRS6B (P33298)
26S proteasome regulatory subunit 6B homolog (Protein YNT1) (Tat-binding homolog 2)
Gene: RPT3

Interactor 2: RPN3 (P40016)
26S proteasome regulatory subunit RPN3
Gene: RPN3

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	11805837, 9724628, 37968396, 22940862
Identification Methods	anti tag coimmunoprecipitation, affinity chromatography technology, biochemical
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0006511 - ubiquitin-dependent protein catabolic process GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 428 Sc			1 523
+	At
		1339246 PRS4A_ARATH (44-419): 3.53e-159: 457: 46.83		PSD3B_ARATH (3-513): 0: 518: 30.95
+	At
		1338931 PRS4A_ARATH (44-419): 3.53e-159: 457: 46.83		PSD3A_ARATH (3-513): 1.12e-179: 515: 31.21
+	Hs
		198596 PRS4_HUMAN (15-427): 5.03e-128: 378: 44.34		PSMD3_HUMAN (9-513): 0: 546: 30.71
+	Dm
		627122 PRS4_DROME (17-427): 3.74e-136: 399: 44.10		PSMD3_DROME (1-513): 0: 521: 31.40
+	Hs
		198568 PRS6B_HUMAN (1-424): 2.6e-125: 371: 65.57		PSMD3_HUMAN (9-513): 0: 546: 30.71
+	Sc
		766858 PRS4_YEAST (49-410): 4.56e-110: 332: 47.53		RPN3_YEAST (1-523): 0: 582: 100.00
+	Hs
		198600 PRS10_HUMAN (41-426): 2.56e-123: 364: 37.57		PSMD3_HUMAN (9-513): 0: 546: 30.71
+	Hs
		198597 PRS8_HUMAN (30-423): 3.39e-120: 357: 39.59		PSMD3_HUMAN (9-513): 0: 546: 30.71
+	Dm
		627136 Q9V405_DROME (28-424): 1.01e-123: 366: 69.42		PSMD3_DROME (1-513): 0: 521: 31.40
+	Dm
		186101 PRS8_DROME (32-423): 7.65e-123: 364: 40.05		PSMD3_DROME (1-513): 0: 521: 31.40
+	Dm
		627147 Q9W414_DROME (41-426): 1.57e-121: 360: 39.90		PSMD3_DROME (1-513): 0: 521: 31.40