Interactor 1: PRS7 (P33299)
26S proteasome regulatory subunit 7 homolog (Protein CIM5) (Tat-binding homolog 3)
Gene: RPT1

Interactor 2: RPN1 (P38764)
26S proteasome regulatory subunit RPN1 (HMG-CoA reductase degradation protein 2) (Proteasome non-ATPase subunit 1)
Gene: RPN1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.991

The method score is based on:

Property Details
Experiments 11742986, 23562395, 10688918, 19412160, 24013205, 26301997, 16429126, 36621624, 31778111, 15917626, 23644457, 19446322, 10873636, 9741626, 9584156, 16554755, 18467557, 19087962, 19446323, 37968396 and 4 others

more...

Identification Methods two hybrid, pull down, affinity chromatography technology, biochemical, protein complementation assay, x-ray crystallography, anti tag coimmunoprecipitation, dihydrofolate reductase reconstruction, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains AAA_lid_3~RPN1_C, AAA_lid_3~RPN1_RPN2_N
Common GO terms GO:0000502 - proteasome complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0008540 - proteasome regulatory particle, base subcomplex
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 467
Sc

1 993
+ Sc
+ Hs
+ Hs
+ Hs
+ At
+ At
+ At
+ Sp
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs
+ Dm
+ Dm
+ Hs
+ Dm
+ Hs
+ Sc
+ Sc

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Last updated: 15 Jul 2024