HitPredict

Interactor 1: PRS7 (P33299)
26S proteasome regulatory subunit 7 homolog (Protein CIM5) (Tat-binding homolog 3)
Gene: RPT1

Interactor 2: DSK2 (P48510)
Ubiquitin domain-containing protein DSK2
Gene: DSK2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.927

Property	Details
Experiments	17082762, 18995839, 11805328, 20061387, 16712842
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	AAA~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 467 Sc			1 373
+	Dm
		1359291 Q9V405_DROME (60-459): 2.26e-135: 397: 35.50		Q9V3W9_DROME (3-370): 3.84e-54: 185: 14.88
+	Sc
		697067 PRS7_YEAST (1-467): 2.69e-137: 405: 100.00		RAD23_YEAST (2-370): 3.25e-51: 177: 15.25
+	Hs
		730224 PRS7_HUMAN (12-467): 2.4e-131: 388: 70.40		RD23A_HUMAN (1-370): 2.33e-57: 192: 16.92
+	Rn
		1117330 PRS7_RAT (12-467): 6.82e-131: 387: 70.18		RD23B_RAT (3-369): 2.17e-52: 181: 14.38
+	Hs
		730225 PRS7_HUMAN (12-467): 2.4e-131: 388: 70.40		RD23B_HUMAN (3-369): 2.45e-50: 175: 13.70
+	Hs
		798620 PRS6B_HUMAN (43-459): 4.68e-123: 366: 35.49		RD23A_HUMAN (1-370): 2.33e-57: 192: 16.92
+	Rn
		1117333 PRS6B_RAT (43-459): 4.73e-123: 366: 35.49		RD23B_RAT (3-369): 2.17e-52: 181: 14.38
+	Sc
		697104 PRS10_YEAST (29-465): 2.46e-123: 367: 37.07		RAD23_YEAST (2-370): 3.25e-51: 177: 15.25
+	Hs
		798621 PRS6B_HUMAN (43-459): 4.68e-123: 366: 35.49		RD23B_HUMAN (3-369): 2.45e-50: 175: 13.70
+	Xl
		804064 PRS8_XENLA (81-464): 1.27e-124: 372: 44.53		BAG6A_XENLA (3-313): 1.38e-42: 160: 19.08
+	Sp
		194878 PRS7_SCHPO (1-465): 1.02e-126: 376: 73.33		UBP6_SCHPO (1-197): 1.25e-34: 134: 16.51
+	Hs
		798608 PRS6B_HUMAN (43-459): 4.68e-123: 366: 35.49		BAG6_HUMAN (2-313): 7.67e-32: 129: 20.74
+	Dm
		1359420 Q9V405_DROME (60-459): 2.26e-135: 397: 35.50		Q9VWD9_DROME (79-367): 2.13e-21: 97.7: 18.86
+	Hs
		730383 PRS7_HUMAN (12-467): 2.4e-131: 388: 70.40		UBQL1_HUMAN (73-370): 3.03e-20: 94.2: 17.61
+	Dm
		1181058 Q7KMQ0_DROME (12-467): 4.56e-129: 382: 68.64		Q9VWD9_DROME (79-367): 2.13e-21: 97.7: 18.86
+	Hs
		730376 PRS7_HUMAN (12-467): 2.4e-131: 388: 70.40		UBQL2_HUMAN (73-370): 4.05e-19: 90.7: 20.25
+	Hs
		730366 PRS7_HUMAN (12-467): 2.4e-131: 388: 70.40		UBQL4_HUMAN (74-370): 4.18e-18: 87.6: 13.64
+	Dm
		1375073 Q9W414_DROME (79-463): 7.34e-124: 367: 43.90		Q9VWD9_DROME (79-367): 2.13e-21: 97.7: 18.86
+	Hs
		798782 PRS6B_HUMAN (43-459): 4.68e-123: 366: 35.49		UBQL1_HUMAN (73-370): 3.03e-20: 94.2: 17.61
+	Hs
		798776 PRS6B_HUMAN (43-459): 4.68e-123: 366: 35.49		UBQL2_HUMAN (73-370): 4.05e-19: 90.7: 20.25