HitPredict

Interactor 1: B2R8Y4 (B2R8Y4)
cDNA, FLJ94117, highly similar to Homo sapiens actinin, alpha 3 (ACTN3), mRNA
Gene: B2R8Y4

Interactor 2: ABI3 (Q9P2A4)
ABI gene family member 3 (New molecule including SH3) (Nesh)
Gene: ABI3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030036 - actin cytoskeleton organization GO:0051015 - actin filament binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 901 Hs			1 366
+	Hs
		993299 ACTN3_HUMAN (1-901): 0: 667: 99.45		ABI3_HUMAN (1-366): 1.12e-87: 270: 100.00
+	Hs
		70397 B2R8Y4_HUMAN (1-901): 0: 670: 100.00		NEBL_HUMAN (13-363): 2.92e-35: 139: 14.13
+	Hs
		282325 ACTN3_HUMAN (1-901): 0: 667: 99.45		NEBL_HUMAN (13-363): 2.92e-35: 139: 14.13
+	Hs
		211580 ACTN4_HUMAN (25-901): 0: 638: 74.49		SRC8_HUMAN (40-363): 2.07e-42: 157: 16.12
+	Hs
		521521 ACTN1_HUMAN (19-901): 0: 675: 78.04		GRB2_HUMAN (312-363): 4.03e-14: 72.7: 28.30
+	Hs
		725677 ACTN2_HUMAN (13-901): 0: 647: 80.09		ABI1_HUMAN (124-363): 7.31e-21: 95.5: 24.49
+	Hs
		211557 ACTN4_HUMAN (25-901): 0: 638: 74.49		GRB2_HUMAN (312-363): 4.03e-14: 72.7: 28.30
+	Hs
		963325 SPTB2_HUMAN (240-767): 3.83e-14: 79.3: 13.23		SRC8_HUMAN (40-363): 2.07e-42: 157: 16.12
+	Hs
		963409 SPTB2_HUMAN (240-767): 3.83e-14: 79.3: 13.23		PACN1_HUMAN (11-363): 5.47e-37: 140: 12.67
+	Hs
		924482 SPTB2_HUMAN (240-767): 3.83e-14: 79.3: 13.23		GRB2_HUMAN (312-363): 4.03e-14: 72.7: 28.30
+	Hs
		963335 SPTB2_HUMAN (240-767): 3.83e-14: 79.3: 13.23		ITSN1_HUMAN (205-363): 8.02e-10: 62.8: 15.85