HitPredict

Interactor 1: PDR5 (P33302)
Pleiotropic ABC efflux transporter of multiple drugs (Pleiotropic drug resistance protein 5) (Suppressor of toxicity of sporidesmin)
Gene: PDR5

Interactor 2: TPO1 (Q07824)
Polyamine transporter 1
Gene: TPO1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.613

Property	Details
Experiments	18467557, 22615397
Identification Methods	protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0071944 - cell periphery
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1511 Sc			1 586
+	Sc
		704020 PDR5_YEAST (1-1511): 0: 1148: 100.00		HXT5_YEAST (62-581): 1.33e-83: 274: 11.41
+	Sc
		690432 PDR5_YEAST (1-1511): 0: 1148: 100.00		HXT1_YEAST (92-581): 3.49e-75: 251: 11.52
+	Sc
		704056 PDR5_YEAST (1-1511): 0: 1148: 100.00		TPO2_YEAST (67-585): 1.61e-72: 245: 29.69
+	Sc
		704038 PDR5_YEAST (1-1511): 0: 1148: 100.00		QDR2_YEAST (85-583): 2.76e-72: 243: 14.21
+	Sc
		693508 SNQ2_YEAST (36-1506): 0: 955: 38.33		TPO1_YEAST (1-586): 8.83e-106: 332: 100.00
+	Sc
		972485 PDR12_YEAST (19-1503): 0: 916: 36.22		TPO1_YEAST (1-586): 8.83e-106: 332: 100.00
+	Sc
		693464 SNQ2_YEAST (36-1506): 0: 955: 38.33		HXT5_YEAST (62-581): 1.33e-83: 274: 11.41
+	Sc
		693502 SNQ2_YEAST (36-1506): 0: 955: 38.33		TPO3_YEAST (69-585): 1.69e-76: 256: 30.53
+	Sc
		690429 SNQ2_YEAST (36-1506): 0: 955: 38.33		HXT1_YEAST (92-581): 3.49e-75: 251: 11.52
+	Sc
		693488 SNQ2_YEAST (36-1506): 0: 955: 38.33		TPO2_YEAST (67-585): 1.61e-72: 245: 29.69
+	Sc
		693474 SNQ2_YEAST (36-1506): 0: 955: 38.33		QDR2_YEAST (85-583): 2.76e-72: 243: 14.21
+	Sc
		752329 PDR12_YEAST (19-1503): 0: 916: 36.22		HXT5_YEAST (62-581): 1.33e-83: 274: 11.41
+	Sc
		690464 PDR12_YEAST (19-1503): 0: 916: 36.22		HXT1_YEAST (92-581): 3.49e-75: 251: 11.52
+	Sc
		861172 PDR12_YEAST (19-1503): 0: 916: 36.22		TPO2_YEAST (67-585): 1.61e-72: 245: 29.69
+	Sc
		774339 PDR12_YEAST (19-1503): 0: 916: 36.22		QDR2_YEAST (85-583): 2.76e-72: 243: 14.21
+	Sc
		675019 PDR12_YEAST (19-1503): 0: 916: 36.22		ITR1_YEAST (68-580): 3.04e-67: 230: 10.97
+	Sc
		972490 PDR12_YEAST (19-1503): 0: 916: 36.22		TPO4_YEAST (94-586): 1.74e-66: 230: 31.05
+	Sc
		746665 PDR12_YEAST (19-1503): 0: 916: 36.22		QDR3_YEAST (367-578): 2.31e-41: 161: 27.10
+	Sc
		752338 AUS1_YEAST (176-1511): 0: 760: 29.99		HXT5_YEAST (62-581): 1.33e-83: 274: 11.41
+	Sc
		675025 AUS1_YEAST (176-1511): 0: 760: 29.99		ITR1_YEAST (68-580): 3.04e-67: 230: 10.97