Interactor 1: MED9 (P33308)
Mediator of RNA polymerase II transcription subunit 9 (Chromosome segregation protein 2) (Mediator complex subunit 9)
Gene: CSE2

Interactor 2: MED21 (P47822)
Mediator of RNA polymerase II transcription subunit 21 (Mediator complex subunit 21) (RNAPII complex component SRB7) (Suppressor of RNA polymerase B 7)
Gene: SRB7

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.90 0.716

The method score is based on:

Property Details
Experiments 11470794, 37968396
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Med21~Med9
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
and 4 others

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Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024