Interactor 1: MED9 (P33308)
Mediator of RNA polymerase II transcription subunit 9 (Chromosome segregation protein 2) (Mediator complex subunit 9)
Gene: CSE2

Interactor 2: MED4 (Q12343)
Mediator of RNA polymerase II transcription subunit 4 (Mediator complex subunit 4)
Gene: MED4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.90 0.925

The method score is based on:

Property Details
Experiments 10688190, 11555651, 11470794, 9812975, 16554755, 19077037, 37968396, 33933450, 21498544, 15477388
Identification Methods two hybrid, affinity chromatography technology, pull down, biochemical, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Med4~Med9
Common GO terms GO:0005634 - nucleus
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
GO:0051123 - RNA polymerase II preinitiation complex assembly
GO:0060261 - positive regulation of transcription initiation by RNA polymerase II
and 1 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024