HitPredict

Interactor 1: SEC3 (P33332)
Exocyst complex component SEC3 (Protein PSL1)
Gene: SEC3

Interactor 2: SSO2 (P39926)
Protein SSO2
Gene: SSO2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.859

Property	Details
Experiments	28112172, 35979953
Identification Methods	affinity chromatography technology, pull down, unspecified method, x-ray crystallography, biochemical
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Sec3-PIP2_bind~Syntaxin
Common GO terms	GO:0005628 - prospore membrane GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0006887 - exocytosis GO:0006893 - Golgi to plasma membrane transport
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1336 Sc			1 295
+	Sc
		699482 SEC3_YEAST (1-1336): 0: 1233: 100.00		SSO1_YEAST (1-270): 9.54e-51: 170: 74.82
+	Hs
		1017828 ITSN2_HUMAN (311-631): 5.32e-26: 118: 18.21		STX4_HUMAN (8-285): 7.06e-53: 176: 20.21
+	Hs
		1017665 MRCKA_HUMAN (108-548): 6.4e-19: 95.6: 12.03		STX4_HUMAN (8-285): 7.06e-53: 176: 20.21
+	Hs
		178587 MRCKA_HUMAN (108-548): 6.4e-19: 95.6: 12.03		STX7_HUMAN (42-265): 1.55e-51: 171: 16.07
+	Hs
		178550 ITSN1_HUMAN (114-451): 8.93e-18: 92.1: 10.76		STX7_HUMAN (42-265): 1.55e-51: 171: 16.07
+	Hs
		1017636 SLMAP_HUMAN (142-673): 6.54e-11: 69.1: 10.57		STX4_HUMAN (8-285): 7.06e-53: 176: 20.21
+	Hs
		1030141 SLMAP_HUMAN (142-673): 6.54e-11: 69.1: 10.57		STX3_HUMAN (20-266): 6.2e-50: 168: 23.14