Interactor 1: PRP8 (P33334)
Pre-mRNA-splicing factor 8
Gene: PRP8

Interactor 2: SN114 (P36048)
Pre-mRNA-splicing factor SNU114 (114 kDa U5 small nuclear ribonucleoprotein component) (Growth inhibitory protein 10)
Gene: SNU114

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 17934474, 11805826, 16429126, 16540695, 32196113, 16554755, 16373487, 25561497, 19854871, 37968396
Identification Methods anti tag coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, x-ray crystallography, pull down, two hybrid
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains EFG_C~PROCN, EFTUD2~PROCN, GTP_EFTU~PROCN
Common GO terms GO:0000244 - spliceosomal tri-snRNP complex assembly
GO:0000387 - spliceosomal snRNP assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex
and 4 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 2413
Sc

1 1008
+ Hs
+ At
+ Hs
+ Dm
+ Sp

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Last updated: 15 Jul 2024