HitPredict

Interactor 1: PRP8 (P33334)
Pre-mRNA-splicing factor 8
Gene: PRP8

Interactor 2: SLT11 (P38241)
Pre-mRNA-splicing factor SLT11 (Extracellular mutant protein 2) (Synthetic lethality with U2 protein 11)
Gene: ECM2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	16429126, 37968396
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005634 - nucleus GO:0017070 - U6 snRNA binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 2413 Sc			1 364
+	Hs
		1159306 PRP8_HUMAN (52-2413): 0: 4464: 61.34		RBM22_HUMAN (10-271): 2.18e-64: 212: 23.13
+	At
		1338937 PRP8A_ARATH (44-2413): 0: 4454: 60.60		C3H4_ARATH (10-271): 2.17e-65: 216: 24.31
+	Dm
		53442 A1Z8U0_DROME (60-2413): 0: 4388: 61.32		Q95RB1_DROME (10-271): 2.04e-57: 194: 22.45