HitPredict

Interactor 1: B2RDW1 (B2RDW1)
Ubiquitin-ribosomal protein eS31 fusion protein
Gene: RPS27A

Interactor 2: UB2E3 (Q969T4)
Ubiquitin-conjugating enzyme E2 E3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E3) (UbcH9) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (Ubiquitin-protein ligase E3)
Gene: UBE2E3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	19549727
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 156 Hs			1 207
+	Hs
		895773 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		UB2D3_HUMAN (61-206): 1.1e-80: 238: 64.38
+	Hs
		896410 RS27A_HUMAN (1-156): 3.55e-76: 225: 100.00		UBE2N_HUMAN (59-206): 3.58e-69: 209: 45.27
+	Hs
		1137415 Q5U5U6_HUMAN (1-76): 6.65e-36: 125: 100.00		UB2E3_HUMAN (1-207): 5.71e-90: 264: 100.00
+	Hs
		895774 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		UB2D3_HUMAN (61-206): 1.1e-80: 238: 64.38
+	Rn
		88580 UBC_RAT (1-119): 1.57e-36: 134: 68.29		UB2D1_RAT (61-206): 9.93e-82: 241: 61.64
+	Mm
		476737 UBC_MOUSE (1-119): 1.07e-36: 135: 67.48		UB2D3_MOUSE (61-206): 1.1e-80: 238: 64.38
+	Dm
		639414 Q9W418_DROME (1-77): 1.7e-34: 127: 100.00		UBCD1_DROME (61-206): 9.93e-82: 241: 64.38
+	At
		1091932 UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81		UBC28_ARATH (61-206): 3.78e-81: 239: 60.96
+	At
		715116 UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81		UBC8_ARATH (61-206): 4.04e-81: 239: 61.64
+	At
		715132 UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81		UBC9_ARATH (61-206): 3.16e-80: 237: 60.27
+	At
		715147 UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81		UBC10_ARATH (61-206): 3.89e-80: 237: 60.27
+	At
		715157 UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81		UBC11_ARATH (61-206): 4.3e-80: 237: 62.33
+	Hs
		896411 RL40_HUMAN (1-125): 5.33e-44: 142: 64.80		UBE2N_HUMAN (59-206): 3.58e-69: 209: 45.27
+	At
		1092090 UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81		UBC36_ARATH (60-207): 2.66e-74: 222: 48.65
+	Rn
		1144263 UBC_RAT (1-119): 1.57e-36: 134: 68.29		UBE2N_RAT (59-206): 1.53e-70: 213: 44.60
+	Mm
		476739 UBC_MOUSE (1-119): 1.07e-36: 135: 67.48		UBE2N_MOUSE (59-206): 3.58e-69: 209: 45.27
+	Dr
		94560 F1QHN6_DANRE (1-77): 3.06e-34: 127: 98.70		Q7T3F3_DANRE (59-206): 2.34e-70: 212: 44.60
+	At
		639385 UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81		UBC1_ARATH (59-204): 3.49e-70: 212: 38.36
+	At
		790155 UBQ3_ARATH (1-77): 2.19e-35: 126: 94.81		UBC2_ARATH (59-204): 2.57e-70: 212: 37.67
+	Hs
		474958 UBB_HUMAN (1-76): 6.65e-36: 125: 100.00		UBE2A_HUMAN (59-204): 1.17e-69: 210: 35.62