HitPredict

Interactor 1: SLA2 (P33338)
Protein SLA2 (Transmembrane protein MOP2)
Gene: SLA2

Interactor 2: ACT (P60010)
Actin (EC 3.6.4.-)
Gene: ACT1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	9159132, 10581178
Identification Methods	cosedimentation through density gradient, affinity chromatography technology, unspecified method
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006897 - endocytosis GO:0030479 - actin cortical patch
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 968 Sc			1 375
+	Hs
		148662 CTRO_HUMAN (216-968): 7.93e-72: 263: 14.38		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Rn
		92841 CTRO_RAT (216-968): 1.16e-67: 250: 13.81		ACTB_RAT (1-375): 0: 601: 88.80
+	Hs
		932473 TLN1_HUMAN (441-963): 1.45e-66: 246: 17.75		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Hs
		255307 HIP1R_HUMAN (3-962): 5.64e-58: 218: 19.98		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Rn
		78223 B5DFK5_RAT (3-962): 8.33e-58: 218: 19.88		ACTB_RAT (1-375): 0: 601: 88.80
+	Mm
		933096 HIP1R_MOUSE (3-962): 1.47e-55: 211: 19.98		ACTS_MOUSE (2-375): 0: 590: 86.90
+	Hs
		891935 MY18A_HUMAN (338-781): 3.03e-11: 70: 14.38		ACTB_HUMAN (1-375): 0: 601: 88.80
+	Hs
		929952 MY18A_HUMAN (338-781): 3.03e-11: 70: 14.38		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Hs
		929869 PLEC_HUMAN (324-957): 2.25e-09: 63.8: 12.88		ACTG_HUMAN (1-375): 0: 600: 89.07
+	Dm
		404232 MYSA_DROME (312-961): 6.46e-11: 68.9: 10.11		ACT6_DROME (2-375): 0: 593: 87.97
+	Hs
		932297 MY18A_HUMAN (338-781): 3.03e-11: 70: 14.38		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Hs
		933030 MY18A_HUMAN (338-781): 3.03e-11: 70: 14.38		ACTS_HUMAN (2-375): 0: 590: 86.90
+	Hs
		725136 MYH10_HUMAN (110-571): 8.39e-11: 68.4: 8.99		ACTC_HUMAN (2-375): 0: 591: 87.17
+	Dm
		361160 MYSA_DROME (312-961): 6.46e-11: 68.9: 10.11		ACT4_DROME (2-375): 0: 587: 86.63
+	Hs
		725135 MYH10_HUMAN (110-571): 8.39e-11: 68.4: 8.99		ACTH_HUMAN (2-375): 0: 587: 86.63
+	Hs
		932171 PLEC_HUMAN (324-957): 2.25e-09: 63.8: 12.88		ACTC_HUMAN (2-375): 0: 591: 87.17