HitPredict

Interactor 1: HSP78 (P33416)
Heat shock protein 78, mitochondrial
Gene: HSP78

Interactor 2: TOR1 (P35169)
Serine/threonine-protein kinase TOR1 (EC 2.7.11.1) (Dominant rapamycin resistance protein 1) (Phosphatidylinositol kinase homolog TOR1) (Target of rapamycin kinase 1)
Gene: TOR1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	36115461, 19536198
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0034605 - cellular response to heat
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 811 Sc			1 2470
+	Sc
		680600 HS104_YEAST (1-809): 0: 554: 40.98		TOR1_YEAST (1-2470): 0: 1922: 100.00
+	Sc
		680551 HS104_YEAST (1-809): 0: 554: 40.98		TOR2_YEAST (32-2470): 0: 1818: 67.45
+	Sc
		705084 HSP78_YEAST (1-799): 0: 644: 100.00		ATR_YEAST (831-2470): 1.45e-173: 595: 15.64
+	Sc
		705083 HSP78_YEAST (1-799): 0: 644: 100.00		ATM_YEAST (823-2470): 4.35e-162: 563: 14.41
+	Sc
		680640 HS104_YEAST (1-809): 0: 554: 40.98		ATR_YEAST (831-2470): 1.45e-173: 595: 15.64
+	Hs
		1327270 CLPB_HUMAN (498-811): 5.49e-70: 246: 35.59		TRRAP_HUMAN (228-1290): 1.52e-09: 66.2: 9.44