HitPredict

Interactor 1: HSP78 (P33416)
Heat shock protein 78, mitochondrial
Gene: HSP78

Interactor 2: SSB2 (P40150)
Ribosome-associated molecular chaperone SSB2 (EC 3.6.4.10) (Heat shock protein SSB2) (Hsp70 chaperone Ssb)
Gene: SSB2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0016887 - ATP hydrolysis activity GO:0042026 - protein refolding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 811 Sc			1 613
+	Sc
		510777 HSP78_YEAST (1-799): 0: 644: 100.00		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		680748 HS104_YEAST (1-809): 0: 554: 40.98		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		510551 HS104_YEAST (1-809): 0: 554: 40.98		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Sc
		605324 HSP78_YEAST (1-799): 0: 644: 100.00		HSP74_YEAST (9-611): 0: 680: 62.15
+	Sc
		449992 HSP78_YEAST (1-799): 0: 644: 100.00		HSP73_YEAST (9-611): 0: 677: 60.66
+	Sc
		605312 HS104_YEAST (1-809): 0: 554: 40.98		HSP74_YEAST (9-611): 0: 680: 62.15
+	Sc
		769622 RIX7_YEAST (357-762): 1.6e-24: 111: 12.26		SSB2_YEAST (1-613): 0: 1122: 100.00
+	Sc
		449950 HS104_YEAST (1-809): 0: 554: 40.98		HSP73_YEAST (9-611): 0: 677: 60.66
+	Sc
		512943 RIX7_YEAST (357-762): 1.6e-24: 111: 12.26		SSB1_YEAST (1-613): 0: 1118: 99.35
+	Hs
		504728 CLPB_HUMAN (498-811): 5.49e-70: 246: 35.59		HSP7C_HUMAN (5-612): 0: 897: 60.00
+	Hs
		871771 CLPB_HUMAN (498-811): 5.49e-70: 246: 35.59		HSP72_HUMAN (4-612): 0: 888: 60.13