HitPredict

Interactor 1: HGB1A (B2RPK0)
Putative high mobility group protein B1-like 1 (High mobility group protein B1 pseudogene 1) (Putative high mobility group protein 1-like 1) (HMG-1L1)
Gene: HMGB1P1

Interactor 2: HMGB1 (P09429)
High mobility group protein B1 (High mobility group protein 1) (HMG-1)
Gene: HMGB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	HMG_box~HMG_box, HMG_box~HMG_box_2, HMG_box_2~HMG_box_2
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0008301 - DNA binding, bending
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 211 Hs			1 215
+	Hs
		449498 HMGB1_HUMAN (1-175): 5.3e-42: 142: 94.86		HMGB1_HUMAN (1-174): 9.92e-46: 152: 100.00
+	Hs
		449550 HMGB1_HUMAN (1-175): 5.3e-42: 142: 94.86		HMGB2_HUMAN (1-187): 7e-43: 145: 82.89
+	Hs
		175740 HMGB1_HUMAN (1-175): 5.3e-42: 142: 94.86		HMGB3_HUMAN (13-181): 1.02e-42: 144: 71.60
+	Hs
		175750 HMGB2_HUMAN (1-186): 5.6e-40: 137: 79.57		HMGB3_HUMAN (13-181): 1.02e-42: 144: 71.60
+	Hs
		449542 HMGB1_HUMAN (1-175): 5.3e-42: 142: 94.86		SP100_HUMAN (25-178): 1.23e-34: 131: 87.66
+	Hs
		617247 HMGB2_HUMAN (1-186): 5.6e-40: 137: 79.57		SP100_HUMAN (25-178): 1.23e-34: 131: 87.66
+	Hs
		449699 HMGB1_HUMAN (1-175): 5.3e-42: 142: 94.86		SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50
+	Hs
		617244 SP100_HUMAN (25-178): 8.6e-32: 123: 83.77		SP100_HUMAN (25-178): 1.23e-34: 131: 87.66
+	Hs
		297488 TOX4_HUMAN (91-175): 4.31e-33: 126: 34.12		SSRP1_HUMAN (53-164): 1.59e-28: 114: 37.50
+	Hs
		297438 TOX4_HUMAN (91-175): 4.31e-33: 126: 34.12		TOX4_HUMAN (91-163): 1.19e-27: 111: 38.36
+	Hs
		817923 TFAM_HUMAN (9-189): 7.63e-34: 122: 19.80		SOX2_HUMAN (3-94): 2.8e-25: 102: 23.91
+	Hs
		297540 TOX4_HUMAN (91-175): 4.31e-33: 126: 34.12		TOX2_HUMAN (91-183): 1.82e-20: 90.6: 26.88
+	Hs
		881795 TFAM_HUMAN (9-189): 7.63e-34: 122: 19.80		SOX10_HUMAN (4-98): 1.86e-21: 93.2: 14.74
+	Hs
		449675 HMGB1_HUMAN (1-175): 5.3e-42: 142: 94.86		TFAM_HUMAN (95-186): 2.95e-09: 57.1: 17.39