HitPredict

Interactor 1: HSP78 (P33416)
Heat shock protein 78, mitochondrial
Gene: HSP78

Interactor 2: PRS8 (Q01939)
26S proteasome regulatory subunit 8 homolog (Protein CIM3) (Protein SUG1) (Tat-binding protein TBY1)
Gene: RPT6

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.793

Property	Details
Experiments	19536198, 22875988
Identification Methods	affinity chromatography technology, two hybrid, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	AAA~AAA, AAA~AAA_lid_3, AAA~Prot_ATP_ID_OB, AAA~AAA_2, AAA~AAA_lid_9, AAA~ClpB_D2-small
Common GO terms	GO:0005524 - ATP binding GO:0016887 - ATP hydrolysis activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 811 Sc			1 405
+	Sc
		705245 HSP78_YEAST (1-799): 0: 644: 100.00		PRS4_YEAST (72-395): 3.99e-106: 321: 49.85
+	Sc
		680937 HS104_YEAST (1-809): 0: 554: 40.98		PRS8_YEAST (1-405): 6.47e-132: 386: 100.00
+	Sc
		680757 HS104_YEAST (1-809): 0: 554: 40.98		PRS4_YEAST (72-395): 3.99e-106: 321: 49.85
+	Sc
		680575 HS104_YEAST (1-809): 0: 554: 40.98		PRS7_YEAST (83-391): 1.16e-104: 318: 51.78
+	Sc
		968088 RIX7_YEAST (357-762): 1.6e-24: 111: 12.26		PRS8_YEAST (1-405): 6.47e-132: 386: 100.00
+	Sc
		703966 RIX7_YEAST (357-762): 1.6e-24: 111: 12.26		PRS7_YEAST (83-391): 1.16e-104: 318: 51.78