HitPredict

Interactor 1: B2RQ57 (B2RQ57)
Tyrosine-protein kinase (EC 2.7.10.2)
Gene: Abl2

Interactor 2: ABI1 (Q8CBW3)
Abl interactor 1 (Abelson interactor 1) (Abi-1) (Ablphilin-1) (Eps8 SH3 domain-binding protein) (Eps8-binding protein) (Spectrin SH3 domain-binding protein 1) (e3B1)
Gene: ABI1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.80	0.662

Property	Details
Experiments	7590237
Identification Methods	affinity chromatography technology, enzymatic study, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_1, SH2~SH3_1, SH3_1~SH3_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1078 Mm			1 481
+	Hs
		789078 ABL2_HUMAN (1-1078): 0: 865: 75.32		ABI1_HUMAN (1-481): 1.34e-109: 336: 93.11
+	Hs
		789094 ABL2_HUMAN (1-1078): 0: 865: 75.32		ABI2_HUMAN (1-481): 2.09e-72: 239: 61.79
+	Mm
		337634 ABL1_MOUSE (74-1078): 0: 723: 50.27		ABI1_MOUSE (1-481): 7.25e-118: 356: 100.00
+	Hs
		337502 ABL1_HUMAN (74-1078): 0: 719: 51.21		ABI1_HUMAN (1-481): 1.34e-109: 336: 93.11
+	Hs
		789066 ABL2_HUMAN (1-1078): 0: 865: 75.32		SRC8_HUMAN (263-475): 1.97e-33: 134: 21.27
+	Hs
		337572 ABL1_HUMAN (74-1078): 0: 719: 51.21		ABI2_HUMAN (1-481): 2.09e-72: 239: 61.79
+	Hs
		523060 SRC_HUMAN (24-556): 0: 572: 38.87		ABI1_HUMAN (1-481): 1.34e-109: 336: 93.11
+	Hs
		433413 YES_HUMAN (22-556): 0: 562: 38.29		ABI1_HUMAN (1-481): 1.34e-109: 336: 93.11
+	Hs
		412258 FYN_HUMAN (57-556): 0: 553: 39.65		ABI1_HUMAN (1-481): 1.34e-109: 336: 93.11
+	Hs
		454841 FGR_HUMAN (33-554): 0: 540: 38.35		ABI1_HUMAN (1-481): 1.34e-109: 336: 93.11
+	Hs
		337590 ABL1_HUMAN (74-1078): 0: 719: 51.21		ASAP1_HUMAN (59-478): 1.09e-35: 143: 16.91
+	Ce
		371307 ABL1_CAEEL (10-978): 0: 593: 32.57		Q10929_CAEEL (1-476): 1.28e-68: 228: 31.74
+	Dm
		337662 ABL_DROME (29-915): 0: 573: 42.92		Q9Y0S9_DROME (1-477): 6.31e-70: 232: 35.98
+	Hs
		523197 SRC_HUMAN (24-556): 0: 572: 38.87		ASAP1_HUMAN (59-478): 1.09e-35: 143: 16.91
+	Hs
		522981 SRC_HUMAN (24-556): 0: 572: 38.87		SRC8_HUMAN (263-475): 1.97e-33: 134: 21.27
+	Hs
		412404 FYN_HUMAN (57-556): 0: 553: 39.65		ASAP1_HUMAN (59-478): 1.09e-35: 143: 16.91
+	Hs
		433350 YES_HUMAN (22-556): 0: 562: 38.29		SRC8_HUMAN (263-475): 1.97e-33: 134: 21.27
+	Mm
		763381 FYN_MOUSE (57-556): 0: 553: 39.65		HCLS1_MOUSE (200-476): 5.2e-30: 124: 22.74
+	Mm
		411921 LCK_MOUSE (98-554): 0: 539: 41.20		HCLS1_MOUSE (200-476): 5.2e-30: 124: 22.74
+	Hs
		454795 FGR_HUMAN (33-554): 0: 540: 38.35		HCLS1_HUMAN (200-476): 2.85e-28: 119: 17.56