HitPredict

Interactor 1: GNAI1 (B2RSH2)
Guanine nucleotide-binding protein G(i) subunit alpha-1 (Adenylate cyclase-inhibiting G alpha protein)
Gene: GNAI1

Interactor 2: PI2R (P43252)
Prostacyclin receptor (Prostaglandin I2 receptor) (PGI receptor) (PGI2 receptor) (Prostanoid IP receptor)
Gene: Ptgir

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11443126
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	7tm_1~G-alpha
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 354 Mm			1 415
+	Hs
		391330 GNAI2_HUMAN (1-354): 3.51e-178: 499: 87.89		TA2R_HUMAN (44-352): 2.27e-86: 268: 31.27
+	Hs
		600873 GNAQ_HUMAN (1-353): 3.49e-167: 472: 52.26		TA2R_HUMAN (44-352): 2.27e-86: 268: 31.27
+	Hs
		429011 GNAI1_HUMAN (1-354): 0: 512: 100.00		ADRB2_HUMAN (16-403): 1.55e-69: 227: 15.14
+	Hs
		428884 GNAI3_HUMAN (1-354): 1.51e-179: 503: 93.79		ADRB2_HUMAN (16-403): 1.55e-69: 227: 15.14
+	Hs
		600866 GNA11_HUMAN (1-353): 1.33e-162: 460: 51.13		TA2R_HUMAN (44-352): 2.27e-86: 268: 31.27
+	Hs
		391305 GNAI2_HUMAN (1-354): 3.51e-178: 499: 87.89		ADRB2_HUMAN (16-403): 1.55e-69: 227: 15.14
+	Hs
		926680 GNAI1_HUMAN (1-354): 0: 512: 100.00		MTR1L_HUMAN (28-411): 1.33e-61: 211: 13.10
+	Mm
		597628 GNA11_MOUSE (1-353): 7.07e-164: 463: 50.85		PI2R_MOUSE (1-415): 5.82e-80: 254: 100.00
+	Hs
		825681 GNAI1_HUMAN (1-354): 0: 512: 100.00		MTR1B_HUMAN (2-363): 1.43e-61: 204: 19.46
+	Hs
		600887 GNA13_HUMAN (2-353): 1.72e-155: 443: 39.17		TA2R_HUMAN (44-352): 2.27e-86: 268: 31.27
+	Hs
		428911 GNAT2_HUMAN (1-354): 8.28e-172: 483: 69.49		ADRB2_HUMAN (16-403): 1.55e-69: 227: 15.14
+	Hs
		444688 GNAI3_HUMAN (1-354): 1.51e-179: 503: 93.79		MTR1B_HUMAN (2-363): 1.43e-61: 204: 19.46
+	Hs
		391355 GNAI2_HUMAN (1-354): 3.51e-178: 499: 87.89		MTR1B_HUMAN (2-363): 1.43e-61: 204: 19.46
+	Hs
		391347 GNAI2_HUMAN (1-354): 3.51e-178: 499: 87.89		OPRD_HUMAN (4-364): 4.93e-61: 203: 13.86
+	Hs
		793174 GNAQ_HUMAN (1-353): 3.49e-167: 472: 52.26		PI2R_HUMAN (29-415): 1.78e-68: 223: 78.87
+	Hs
		450979 GNAO_HUMAN (1-354): 4.45e-175: 491: 72.11		OPRM_HUMAN (15-384): 1.42e-60: 203: 13.56
+	Hs
		450984 GNAO_HUMAN (1-354): 4.45e-175: 491: 72.11		OPRD_HUMAN (4-364): 4.93e-61: 203: 13.86
+	Bt
		362125 GNAT1_BOVIN (1-354): 8.16e-169: 475: 67.80		OPSD_BOVIN (4-361): 3.4e-61: 203: 15.98
+	Rn
		444647 GNAI3_RAT (1-354): 4.08e-178: 499: 93.50		AA3R_RAT (53-320): 8.05e-15: 76.6: 18.52
+	Rn
		391301 GNAI2_RAT (1-354): 1.06e-177: 498: 88.17		AA3R_RAT (53-320): 8.05e-15: 76.6: 18.52