Interactor 1: MRP1 (P33527)
Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter)
Gene: ABCC1

Interactor 2: MRP1 (P33527)
Multidrug resistance-associated protein 1 (EC 7.6.2.2) (ATP-binding cassette sub-family C member 1) (Glutathione-S-conjugate-translocating ATPase ABCC1) (EC 7.6.2.3) (Leukotriene C(4) transporter) (LTC4 transporter)
Gene: ABCC1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.825

The method score is based on:

Property Details
Experiments 17264072, 21090806
Identification Methods affinity chromatography technology, biochemical, pull down
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ABC_membrane~ABC_membrane, ABC_membrane~ABC_tran, ABC_tran~ABC_tran
Common GO terms GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0006691 - leukotriene metabolic process
GO:0006805 - xenobiotic metabolic process
GO:0008559 - ABC-type xenobiotic transporter activity
and 38 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 1531
Hs

1 1531
+ Hs
+ Sc
+ Rn
+ Hs
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024