HitPredict

Interactor 1: CKS2 (P33552)
Cyclin-dependent kinases regulatory subunit 2 (CKS-2)
Gene: CKS2

Interactor 2: FZR1 (Q9UM11)
Fizzy-related protein homolog (Fzr) (CDC20-like protein 1) (Cdh1/Hct1 homolog) (hCDH1)
Gene: FZR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 33306668, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007346 - regulation of mitotic cell cycle GO:0051301 - cell division
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 79 Hs			1 496
+	Hs
		895463 CKS1_HUMAN (1-79): 1.09e-39: 127: 81.01		FZR1_HUMAN (319-495): 6.65e-25: 109: 18.68
+	At
		1228253 CKS2_ARATH (5-78): 2.49e-39: 126: 66.22		FZR3_ARATH (315-495): 1.15e-19: 93.5: 18.48
+	At
		188159 CKS1_ARATH (5-73): 5.91e-38: 123: 68.12		FZR3_ARATH (315-495): 1.15e-19: 93.5: 18.48
+	At
		1258613 CKS2_ARATH (5-78): 2.49e-39: 126: 66.22		FZR1_ARATH (319-495): 8.99e-18: 87.7: 21.67
+	Hs
		895422 CKS1_HUMAN (1-79): 1.09e-39: 127: 81.01		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67
+	Hs
		706800 CKS2_HUMAN (1-79): 8.58e-38: 122: 100.00		CDC20_HUMAN (395-494): 7.34e-10: 63: 16.67