HitPredict

Interactor 1: DCA13 (P33750)
Protein SOF1 (U3 small nucleolar RNA-associated protein SOF1) (U3 snoRNA-associated protein SOF1)
Gene: SOF1

Interactor 2: UBP10 (P53874)
Ubiquitin carboxyl-terminal hydrolase 10 (EC 3.4.19.12) (Deubiquitinating enzyme 10) (Disrupter of telomere silencing protein 4) (Ubiquitin thioesterase 10) (Ubiquitin-specific-processing protease 10)
Gene: UBP10

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	1.00	0.698

Property	Details
Experiments	18467557
Identification Methods	protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UCH~WD40
Common GO terms	GO:0005730 - nucleolus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 489 Sc			1 792
+	Sc
		630881 NLE1_YEAST (155-482): 2.05e-57: 200: 11.60		UBP10_YEAST (1-770): 5.85e-168: 506: 100.00
+	Hs
		1346277 DCA13_HUMAN (1-453): 7.02e-105: 321: 44.59		UBP36_HUMAN (250-785): 2.88e-78: 275: 18.85
+	Hs
		271161 FBXW7_HUMAN (148-441): 5.72e-64: 222: 12.77		UBP2_HUMAN (167-737): 1.17e-99: 322: 15.68
+	Hs
		1058268 FBXW7_HUMAN (148-441): 5.72e-64: 222: 12.77		UBP10_HUMAN (11-734): 1.63e-93: 312: 15.96
+	Hs
		1281441 FBXW7_HUMAN (148-441): 5.72e-64: 222: 12.77		UBP36_HUMAN (250-785): 2.88e-78: 275: 18.85
+	Hs
		903231 WDR5_HUMAN (5-204): 4.35e-24: 104: 11.22		UBP10_HUMAN (11-734): 1.63e-93: 312: 15.96
+	Hs
		903417 WDR5_HUMAN (5-204): 4.35e-24: 104: 11.22		UBP7_HUMAN (162-786): 4e-90: 308: 13.21
+	Hs
		1346960 NLE1_HUMAN (288-485): 3.92e-34: 135: 14.22		UBP36_HUMAN (250-785): 2.88e-78: 275: 18.85
+	Hs
		903571 WDR5_HUMAN (5-204): 4.35e-24: 104: 11.22		UBP36_HUMAN (250-785): 2.88e-78: 275: 18.85
+	Hs
		1288358 SNR40_HUMAN (3-145): 5.57e-17: 84.1: 12.03		UBP36_HUMAN (250-785): 2.88e-78: 275: 18.85
+	Hs
		1288312 SNR40_HUMAN (3-145): 5.57e-17: 84.1: 12.03		UBP42_HUMAN (261-776): 8.85e-76: 270: 17.66
+	Hs
		1121184 SNR40_HUMAN (3-145): 5.57e-17: 84.1: 12.03		UBP39_HUMAN (135-737): 8.42e-77: 260: 13.66
+	Hs
		1281492 FBXW7_HUMAN (148-441): 5.72e-64: 222: 12.77		UBP20_HUMAN (462-738): 2.62e-24: 111: 30.51
+	Hs
		245635 TBL1X_HUMAN (146-481): 9.23e-55: 194: 14.25		UBP44_HUMAN (454-732): 3.22e-15: 81.6: 24.68
+	Hs
		1318177 TBL1R_HUMAN (151-481): 4.21e-55: 193: 15.49		UBP44_HUMAN (454-732): 3.22e-15: 81.6: 24.68
+	Hs
		903505 WDR5_HUMAN (5-204): 4.35e-24: 104: 11.22		UBP44_HUMAN (454-732): 3.22e-15: 81.6: 24.68
+	Dm
		1373200 FBXW7_DROME (289-466): 1.42e-21: 100: 13.68		UBP36_DROME (363-527): 8.17e-09: 61.2: 27.17