HitPredict

Interactor 1: DCA13 (P33750)
Protein SOF1 (U3 small nucleolar RNA-associated protein SOF1) (U3 snoRNA-associated protein SOF1)
Gene: SOF1

Interactor 2: RRP9 (Q06506)
Ribosomal RNA-processing protein 9
Gene: RRP9

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	12150911, 37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Sof1~WD40, WD40~WD40
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0030490 - maturation of SSU-rRNA GO:0030686 - 90S preribosome GO:0032040 - small-subunit processome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 489 Sc			1 573
+	Hs
		215391 DCA13_HUMAN (1-453): 7.02e-105: 321: 44.59		U3IP2_HUMAN (5-356): 6.66e-18: 88.5: 14.91
+	Hs
		1016334 DCA13_HUMAN (1-453): 7.02e-105: 321: 44.59		TBL3_HUMAN (428-572): 9.97e-17: 85.9: 11.77
+	Hs
		903418 FBXW7_HUMAN (148-441): 5.72e-64: 222: 12.77		WDR5_HUMAN (394-572): 8.9e-36: 138: 12.12
+	Hs
		1281292 FBXW7_HUMAN (148-441): 5.72e-64: 222: 12.77		FBXW7_HUMAN (393-569): 2.36e-29: 125: 16.06
+	Hs
		1240442 POC1A_HUMAN (161-476): 1.39e-67: 223: 12.77		POC1B_HUMAN (413-572): 1.03e-24: 109: 10.18
+	Hs
		245630 TBL1Y_HUMAN (89-448): 5.91e-65: 220: 12.70		TBL1X_HUMAN (382-572): 1.94e-23: 106: 12.31
+	Sc
		630844 NLE1_YEAST (155-482): 2.05e-57: 200: 11.60		NLE1_YEAST (433-573): 3.75e-28: 120: 12.84
+	Hs
		245546 TBL1X_HUMAN (146-481): 9.23e-55: 194: 14.25		TBL1X_HUMAN (382-572): 1.94e-23: 106: 12.31
+	Hs
		245633 TBL1R_HUMAN (151-481): 4.21e-55: 193: 15.49		TBL1X_HUMAN (382-572): 1.94e-23: 106: 12.31
+	Hs
		903551 NLE1_HUMAN (288-485): 3.92e-34: 135: 14.22		WDR5_HUMAN (394-572): 8.9e-36: 138: 12.12
+	Hs
		1346954 NLE1_HUMAN (288-485): 3.92e-34: 135: 14.22		NLE1_HUMAN (385-573): 1.19e-27: 118: 12.69
+	Hs
		903349 WDR5B_HUMAN (3-204): 6.36e-24: 104: 9.76		WDR5_HUMAN (394-572): 8.9e-36: 138: 12.12
+	Sp
		999842 TUP11_SCHPO (35-254): 9.5e-39: 150: 12.30		TUP12_SCHPO (459-572): 2.89e-13: 74.7: 16.26
+	Sp
		999838 TUP11_SCHPO (35-254): 9.5e-39: 150: 12.30		TUP11_SCHPO (70-206): 7.78e-11: 67: 8.33
+	Hs
		1146788 WDR83_HUMAN (59-381): 2.11e-26: 111: 18.49		A16L1_HUMAN (380-562): 5.62e-22: 102: 11.74
+	Hs
		1288273 WDR83_HUMAN (59-381): 2.11e-26: 111: 18.49		SNR40_HUMAN (69-262): 7.57e-20: 93.2: 8.62
+	Dm
		1358859 WDS_DROME (5-208): 1.88e-25: 109: 11.01		FBXW7_DROME (229-508): 3.82e-17: 87.4: 19.32
+	Hs
		215331 WDR5_HUMAN (5-204): 4.35e-24: 104: 11.22		U3IP2_HUMAN (5-356): 6.66e-18: 88.5: 14.91
+	Dm
		1358845 WDS_DROME (5-208): 1.88e-25: 109: 11.01		WDS_DROME (76-267): 3.05e-15: 79.3: 10.63
+	Hs
		209416 WDR5_HUMAN (5-204): 4.35e-24: 104: 11.22		PLRG1_HUMAN (233-542): 6.65e-16: 82.8: 15.48