Interactor 1: NPL4 (P33755)
Nuclear protein localization protein 4 (HMG-CoA reductase degradation protein 4)
Gene: NPL4

Interactor 2: UBX2 (Q04228)
UBX domain-containing protein 2 (Secretion lowering protein 1)
Gene: UBX2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.55 0.682

The method score is based on:

Property Details
Experiments 16919153, 21211725, 16179952, 37968396, 16429126
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000837 - Doa10p ubiquitin ligase complex
GO:0000839 - Hrd1p ubiquitin ligase ERAD-L complex
GO:0036503 - ERAD pathway
GO:0043130 - ubiquitin binding
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
and 1 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024