HitPredict

Interactor 1: APBA1 (B2RUJ5)
Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1)
Gene: APBA1

Interactor 2: LIN7C (O88952)
Protein lin-7 homolog C (Lin-7C) (mLin7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	9822620, 16186258
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~PDZ, PDZ~PID
Common GO terms	GO:0030165 - PDZ domain binding GO:0098978 - glutamatergic synapse
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 842 Mm			1 197
+	Hs
		970742 APBA1_HUMAN (1-842): 0: 915: 92.99		LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00
+	Hs
		970739 APBA1_HUMAN (1-842): 0: 915: 92.99		LIN7B_HUMAN (1-196): 4.81e-55: 175: 84.69
+	Hs
		158274 APBA1_HUMAN (1-842): 0: 915: 92.99		LIN7A_HUMAN (6-194): 4.87e-51: 166: 80.42
+	Hs
		159194 APBA1_HUMAN (1-842): 0: 915: 92.99		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Hs
		942327 APBA1_HUMAN (1-842): 0: 915: 92.99		DLG4_HUMAN (59-195): 2.19e-23: 98.7: 26.76
+	Hs
		970694 APBA1_HUMAN (1-842): 0: 915: 92.99		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Ce
		184638 LIN10_CAEEL (359-842): 5.78e-118: 383: 50.00		Q9U245_CAEEL (3-195): 2.33e-42: 142: 67.88
+	Dm
		677693 Q5BI79_DROME (457-842): 2.09e-112: 378: 62.53		DLG1_DROME (57-176): 1.06e-14: 73.6: 28.00
+	Hs
		158292 RIMS1_HUMAN (282-747): 1.15e-65: 241: 16.03		LIN7A_HUMAN (6-194): 4.87e-51: 166: 80.42
+	Hs
		1125512 RIMS1_HUMAN (282-747): 1.15e-65: 241: 16.03		PDZ11_HUMAN (91-175): 4.41e-13: 65.5: 45.35
+	Rn
		1144014 DLG1_RAT (639-839): 1.32e-45: 178: 20.00		DLG2_RAT (23-196): 1.1e-25: 105: 23.63
+	Rn
		677787 DLG1_RAT (639-839): 1.32e-45: 178: 20.00		DLG4_RAT (59-195): 2.17e-23: 98.7: 26.76
+	Rn
		1144010 DLG1_RAT (639-839): 1.32e-45: 178: 20.00		DLG3_RAT (60-164): 3.16e-21: 92.5: 32.73
+	Dm
		677695 SCRIB_DROME (625-824): 2.86e-40: 163: 23.11		DLG1_DROME (57-176): 1.06e-14: 73.6: 28.00
+	Mm
		1143467 DLG2_MOUSE (516-823): 3.57e-26: 117: 13.61		DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76
+	Hs
		942349 DLG2_HUMAN (516-740): 7.32e-25: 113: 14.91		DLG4_HUMAN (59-195): 2.19e-23: 98.7: 26.76
+	Hs
		1021501 DLG2_HUMAN (516-740): 7.32e-25: 113: 14.91		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Mm
		936188 DLG2_MOUSE (516-823): 3.57e-26: 117: 13.61		DLG3_MOUSE (60-164): 3.31e-21: 92.5: 32.73
+	Hs
		1077285 DLG2_HUMAN (516-740): 7.32e-25: 113: 14.91		DLG3_HUMAN (74-164): 2.8e-20: 89.8: 35.42